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  3. EMX1

EMX1 (Empty spiracles homeobox 1)

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The Function of EMX1

Transcription factor, which in cooperation with EMX2, acts to generate the boundary between the roof and archipallium in the developing brain. May function in combinations with OTX1/2 to specify cell fates in the developing central nervous system.

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Protein names

Recommended name:

Homeobox protein EMX1

Alternative name(s):

Empty spiracles homolog 1
Empty spiracles-like protein 1

EMX1 SNPs

    To see your genotype, you should be logged in and have a file with your genotype uploaded.

  1. RS2077586 (EMX1) ??

Top Gene-Substance Interactions

Substances That Increase EMX1

Substances Interaction Organism Category

Substances That Decrease EMX1

Substances Interaction Organism Category

Conditions with Increased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Conditions with Decreased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Technical

The following transcription factors affect gene expression:

  • AhR
  • Nkx2-2
  • GATA-1
  • Roaz

Tissue specificity:

Cerebral cortex.

Molecular Function:

  • Sequence-Specific Dna Binding

Biological Processes:

  • Brain Morphogenesis
  • Cerebral Cortex Neuron Differentiation
  • Cerebral Cortex Regionalization
  • Homeostasis Of Number Of Cells
  • In Utero Embryonic Development
  • Neuroepithelial Cell Differentiation
  • Neuron Projection Extension
  • Post-Embryonic Development
  • Radial Glial Cell Differentiation
  • Regulation Of Oligodendrocyte Progenitor Proliferation
  • Regulation Of Transcription, Dna-Templated
*synonyms

Synonyms/Aliases/Alternative Names of the Gene:

hypothetical protein| empty spiracles homeobox 1, gene 1| empty spiracles homolog 1| empty spiracles-like protein 1| emx1.1| Emx1 transcription factor| GW7_03300| H920_17442| Homeobox protein EMX1| homeotic protein empty spiracles-like| M91_12362| N303_05312| N307_13993| PAL_GLEAN10008504| RGD1564002| TREES_T100006678| UY3_18680| XEmx1| emx1

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