Summary of EMILIN1
This gene encodes a protein that plays a role in the development of elastic tissues of blood vessels and in the heart and lungs (R).
The Function of EMILIN1
May be responsible for anchoring smooth muscle cells to elastic fibers, and may be involved not only in the formation of the elastic fiber, but also in the processes that regulate vessel assembly. Has cell adhesive capacity.
Protein names
Recommended name:
EMILIN-1Alternative name(s):
Elastin microfibril interface-located protein 1Elastin microfibril interfacer 1
- RS2011616 (EMILIN1) ??
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Top Gene-Substance Interactions
Substances That Increase EMILIN1
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Substances That Decrease EMILIN1
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Conditions with Increased Gene Activity
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Conditions with Decreased Gene Activity
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Technical
The following transcription factors affect gene expression:
Tissue specificity:
Distributed in tissues where resilience and elastic recoil are prominent. Highest levels in the adult small intestine, aorta, lung, uterus, and appendix and in the fetal spleen, kidney, lung, and heart; intermediate expression was detected in adult liver, ovary, colon, stomach, lymph node and spleen; adult heart, bladder, prostate, adrenal gland, mammary gland, placenta and kidney showed low expression whereas a series of other adult tissues, including skeletal muscle and different regions of adult brain show no expression.