Summary of EHBP1
This gene encodes a protein that plays a role in endocytic trafficking and actin reorganization. It is associated with prostate cancer (R).
The Function of EHBP1
May play a role in actin reorganization. Links clathrin-mediated endocytosis to the actin cytoskeleton.
Protein names
Recommended name:
EH domain-binding protein 1- RS11688816 (EHBP1) ??
- RS2430386 (EHBP1) ??
- RS2710642 (EHBP1) ??
- RS2710646 (EHBP1) ??
- RS721048 (EHBP1) ??
To see your genotype, you should be logged in and have a file with your genotype uploaded.
Top Gene-Substance Interactions
EHBP1 Interacts with These Diseases
Disease | Score |
Substances That Increase EHBP1
Substances | Interaction | Organism | Category |
Substances That Decrease EHBP1
Substances | Interaction | Organism | Category |
Advanced Summary
Covered on Genetics Home Reference: prostate cancerFrom NCBI Gene: Prostate cancer, hereditary, 12From UniProt: Prostate cancer, hereditary, 12 (HPC12): A condition associated with familial predisposition to cancer of the prostate. Most prostate cancers are adenocarcinomas that develop in the acini of the prostatic ducts. Other rare histopathologic types of prostate cancer that occur in approximately 5% of patients include small cell carcinoma, mucinous carcinoma, prostatic ductal carcinoma, transitional cell carcinoma, squamous cell carcinoma, basal cell carcinoma, adenoid cystic carcinoma (basaloid), signet-ring cell carcinoma and neuroendocrine carcinoma. [MIM:611868]
From NCBI Gene: This gene encodes an Eps15 homology domain binding protein. The encoded protein may play a role in endocytic trafficking. A single nucleotide polymorphism in this gene is associated with an aggressive form of prostate cancer. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010] From UniProt: May play a role in actin reorganization. Links clathrin-mediated endocytosis to the actin cytoskeleton.
Conditions with Increased Gene Activity
Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
---|
Conditions with Decreased Gene Activity
Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
---|