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  3. E2F5

E2F5 (E2F transcription factor 5)

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The Function of E2F5

Transcriptional activator that binds to E2F sites, these sites are present in the promoter of many genes whose products are involved in cell proliferation. May mediate growth factor-initiated signal transduction. It is likely involved in the early responses of resting cells to growth factor stimulation. Specifically required for multiciliate cell differentiation: together with MCIDAS and E2F5, binds and activate genes required for centriole biogenesis.

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Protein names

Recommended name:

Transcription factor E2F5

Short name:

E2F-5

E2F5 SNPs

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  1. RS2403083 (E2F5) ??

Top Gene-Substance Interactions

Substances That Increase E2F5

Substances Interaction Organism Category

Substances That Decrease E2F5

Substances Interaction Organism Category

Conditions with Increased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Conditions with Decreased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Technical

The following transcription factors affect gene expression:

  • NF-kappaB
  • p53
  • Egr-1
  • NF-kappaB1

Molecular Function:

  • Dna Binding
  • Transcription Factor Activity, Sequence-Specific Dna Binding
  • Transcription Factor Binding

Biological Processes:

  • Animal Organ Morphogenesis
  • Cell Projection Organization
  • Positive Regulation Of Transcription From Rna Polymerase Ii Promoter
  • Regulation Of Cell Cycle
  • Transcription, Dna-Templated
*synonyms

Synonyms/Aliases/Alternative Names of the Gene:

hypothetical protein| A306_00164| Anapl_14668| AS27_10520| AS28_00372| E2F4| E2f-5| E2F transcription factor 5, p130-binding| E2F transcription factor 5, p130-binding protein| MDA_GLEAN10003803| N301_02683| N302_07836| N303_08092| N305_10118| N306_08003| N309_15639| N310_03886| N311_04066| N312_08909| N321_13119| N322_10839| N324_09817| N326_11437| N327_05381| N328_01317| N330_09683| N331_11854| N332_07514| N333_06732| N335_11992| N339_10667| N340_03385| PAL_GLEAN10019430| transcription factor E2F5| TREES_T100017162| Y1Q_020217| Y956_06957| e2f5

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