The Function of DUSP5
Dual specificity protein phosphatase; active with phosphotyrosine, phosphoserine and phosphothreonine residues. The highest relative activity is toward ERK1.
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Protein names
Recommended name:
Dual specificity protein phosphatase 5Alternative name(s):
Dual specificity protein phosphatase hVH3Top Gene-Substance Interactions
DUSP5 Interacts with These Diseases
| Disease | Score |
Substances That Increase DUSP5
| Substances | Interaction | Organism | Category |
Substances That Decrease DUSP5
| Substances | Interaction | Organism | Category |
Conditions with Increased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
|---|
Conditions with Decreased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
|---|
Technical
The following transcription factors affect gene expression:
Gene Pathways:
Molecular Function:
- Map Kinase Tyrosine/Serine/Threonine Phosphatase Activity
- Phosphatase Activity
- Protein Tyrosine/Serine/Threonine Phosphatase Activity
- Protein Tyrosine Phosphatase Activity
Biological Processes:
- Activation Of Mapk Activity
- Dephosphorylation
- Endoderm Formation
- Mapk Cascade
- Peptidyl-Threonine Dephosphorylation
- Peptidyl-Tyrosine Dephosphorylation
- Protein Dephosphorylation