• Navigation
  • Register My DNA Kit
  • Features
  • Pricing
  • FAQ
  • About
  • Labs
  • Login
  • Get started
  1. Home
  2. Genes
  3. CXCR5

CXCR5 (C-X-C motif chemokine receptor 5)

Loading...

Summary of CXCR5

This gene encodes a multi-pass membrane protein and is involved in B cell migration (R). 

0 users want this gene increased, 0 users want it decreased

The Function of CXCR5

Cytokine receptor that binds to B-lymphocyte chemoattractant (BLC). Involved in B-cell migration into B-cell follicles of spleen and Peyer patches but not into those of mesenteric or peripheral lymph nodes. May have a regulatory function in Burkitt lymphoma (BL) lymphomagenesis and/or B-cell differentiation.

Protein names

Recommended name:

C-X-C chemokine receptor type 5

Short name:

CXC-R5

Alternative name(s):

CXCR-5
Burkitt lymphoma receptor 1
Monocyte-derived receptor 15
MDR-15
CD antigen CD185

CXCR5 SNPs

    To see your genotype, you should be logged in and have a file with your genotype uploaded.

  1. RS10790268 (CXCR5) ??
  2. RS4938573 (CXCR5) ??
  3. RS630923 (CXCR5) ??
  4. RS638893 (CXCR5) ??
  5. RS6421571 (CXCR5) ??

Top Gene-Substance Interactions

Substances That Increase CXCR5

Substances Interaction Organism Category

Substances That Decrease CXCR5

Substances Interaction Organism Category

Conditions with Increased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Conditions with Decreased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Technical

The following transcription factors affect gene expression:

  • STAT1
  • STAT1beta
  • STAT1alpha

Tissue specificity:

Expression in mature B-cells and Burkitt lymphoma cells.

Gene Pathways:

  • Signal Transduction
  • Cytokine-cytokine receptor interaction
  • Chemokine signaling pathway

Molecular Function:

  • C-X-C Chemokine Receptor Activity
  • G-Protein Coupled Receptor Activity

Biological Processes:

  • B Cell Activation
  • G-Protein Coupled Receptor Signaling Pathway
  • Immune Response
  • Leukocyte Chemotaxis
  • Lymph Node Development
  • Movement Of Cell Or Subcellular Component
  • Positive Regulation Of Cytokinesis
  • Chemotaxis
*synonyms

Synonyms/Aliases/Alternative Names of the Gene:

hypothetical protein| chemokine receptor| chemokine receptor 5| A306_14294| Anapl_06760| blr1| Burkitt lymphoma receptor 1| Burkitt lymphoma receptor 1, GTP-binding protein| Burkitt lymphoma receptor 1, GTP binding protein (chemokine (C-X-C motif) receptor 5)| burkitt lymphoma receptor 1 homolog| CB1_000200035| CD185| chemochine (C-X-C motif) receptor 5| chemokine (C-X-C motif) receptor 5| CRL1| C-X-C chemokine receptor type 5| CXC-R5| CXCR-5| EGK_06966| Gpcr6| GW7_18670| H920_07503| M91_09726| MDR15| MDR-15| monocyte-derived receptor 15| neurolymphatic receptor| NLR| PAL_GLEAN10001967| PANDA_019884| TREES_T100013285| UY3_09469| Y1Q_017859| cxcr5

Policies

  • Terms of Service
  • Platform Consent
  • Privacy Policy
  • Disclaimer

About

  • Customer Support
  • Our Team
  • Affiliate Program

Navigation

  • Homepage
  • DNA Wellness Reports
  • Personalized Genetics Blog
  • Register your DNA Test Kit
  • Login
  • Careers
GET STARTED
  • SelfDecode is a personalized health report service, which enables users to obtain detailed information and reports based on their genome. SelfDecode does not treat, diagnose or cure any conditions, but is for informational and educational purposes alone.
SelfDecode © 2021 All Rights Reserved