• Navigation
  • Register My DNA Kit
  • Features
  • Pricing
  • FAQ
  • About
  • Labs
  • Login
  • Get started
  1. Home
  2. Genes
  3. CXCL9

CXCL9 (C-X-C motif chemokine ligand 9)

Loading...

Summary of CXCL9

Functions as an antimicrobial gene (kills pathogens). It is believed to be involved in T cell trafficking. [R]

0 users want this gene increased, 0 users want it decreased

The Function of CXCL9

Cytokine that affects the growth, movement, or activation state of cells that participate in immune and inflammatory response. Chemotactic for activated T-cells. Binds to CXCR3.

Protein names

Recommended name:

C-X-C motif chemokine 9

Short name:

MIG

Alternative name(s):

Gamma-interferon-induced monokine
Monokine induced by interferon-gamma
HuMIG
Small-inducible cytokine B9

CXCL9 SNPs

    To see your genotype, you should be logged in and have a file with your genotype uploaded.

  1. RS10336 (CXCL9) ??

Top Gene-Substance Interactions

CXCL9 Interacts with These Diseases

Disease Score

Substances That Increase CXCL9

Substances Interaction Organism Category

Substances That Decrease CXCL9

Substances Interaction Organism Category

Conditions with Increased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Conditions with Decreased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Technical

The following transcription factors affect gene expression:

  • NF-kappaB
  • p53
  • AhR
  • NF-kappaB1
  • IRF-1
  • IRF-2

Gene Pathways:

  • Signal Transduction
  • Cytokine-cytokine receptor interaction
  • Toll-like receptor signaling pathway
  • Chemokine signaling pathway

Induction:

By IFNG/IFN-gamma. The induction is enhanced by TNF in dermal fibroblasts and vein endothelial cells.

Molecular Function:

  • Chemokine Activity
  • Cxcr3 Chemokine Receptor Binding
  • Cytokine Activity

Biological Processes:

  • Cell-Cell Signaling
  • Cellular Defense Response
  • Chemokine-Mediated Signaling Pathway
  • Chemotaxis
  • Defense Response
  • Defense Response To Virus
  • G-Protein Coupled Receptor Signaling Pathway
  • Immune Response
  • Inflammatory Response
  • Positive Regulation Of Camp-Mediated Signaling
  • Positive Regulation Of Camp Metabolic Process
  • Positive Regulation Of Leukocyte Chemotaxis
  • Positive Regulation Of Myoblast Differentiation
  • Positive Regulation Of Myoblast Fusion
  • Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol
  • Regulation Of Cell Proliferation
  • Response To Lipopolysaccharide
  • Signal Transduction
*synonyms

Synonyms/Aliases/Alternative Names of the Gene:

hypothetical protein| CMK| chemokine (C-X-C motif) ligand 9| chemokine C-X-C motif ligand 9| chemokine ligand 9| crg-10| C-X-C motif chemokine 9| gamma interferon-induced monokine| gamma-interferon-induced monokine| H920_03517| Humig| interferon-gamma induced monokine CXCL9| M119| MIG| monokine induced by gamma interferon| monokine induced by interferon gamma| monokine induced by interferon-gamma| MuMIG| PAL_GLEAN10012292| PANDA_014180| protein m119| Scyb9| small inducible cytokine B9| small-inducible cytokine B9| small inducible cytokine B subfamily (Cys-X-Cys), member 9| TREES_T100019214| cxcl9

Policies

  • Terms of Service
  • Platform Consent
  • Privacy Policy
  • Disclaimer

About

  • Customer Support
  • Our Team
  • Affiliate Program

Navigation

  • Homepage
  • DNA Wellness Reports
  • Personalized Genetics Blog
  • Register your DNA Test Kit
  • Login
  • Careers
GET STARTED
  • SelfDecode is a personalized health report service, which enables users to obtain detailed information and reports based on their genome. SelfDecode does not treat, diagnose or cure any conditions, but is for informational and educational purposes alone.
SelfDecode © 2021 All Rights Reserved