• Navigation
  • Register My DNA Kit
  • Features
  • Pricing
  • FAQ
  • About
  • Labs
  • Login
  • Get started
  1. Home
  2. Genes
  3. CXCL6

CXCL6 (C-X-C motif chemokine ligand 6)

Loading...

The Function of CXCL6

Chemotactic for neutrophil granulocytes. Signals through binding and activation of its receptors (CXCR1 and CXCR2). In addition to its chemotactic and angiogenic properties, it has strong antibacterial activity against Gram-positive and Gram-negative bacteria (90-fold-higher when compared to CXCL5 and CXCL7).

0 users want this gene increased, 0 users want it decreased

Protein names

Recommended name:

C-X-C motif chemokine 6

Short name:

CKA-3

Alternative name(s):

Chemokine alpha 3
Granulocyte chemotactic protein 2
GCP-2
Small-inducible cytokine B6

Top Gene-Substance Interactions

CXCL6 Interacts with These Diseases

Disease Score

Substances That Increase CXCL6

Substances Interaction Organism Category

Substances That Decrease CXCL6

Substances Interaction Organism Category

Conditions with Increased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Conditions with Decreased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Technical

The following transcription factors affect gene expression:

  • NF-kappaB
  • CUTL1
  • NF-kappaB1
  • TBP
  • c-Rel
  • TFIID
  • NF-kappaB2
  • RelA

Gene Pathways:

  • Signal Transduction
  • Cytokine-cytokine receptor interaction
  • Chemokine signaling pathway
  • Rheumatoid arthritis

Molecular Function:

  • Chemokine Activity
  • Cxcr Chemokine Receptor Binding
  • Heparin Binding

Biological Processes:

  • Cell-Cell Signaling
  • Chemokine-Mediated Signaling Pathway
  • Chemotaxis
  • Defense Response To Bacterium
  • G-Protein Coupled Receptor Signaling Pathway
  • Immune Response
  • Inflammatory Response
  • Neutrophil Mediated Immunity
  • Positive Regulation Of Leukocyte Chemotaxis
  • Regulation Of Cell Proliferation
  • Response To Lipopolysaccharide
  • Signal Transduction
*synonyms

Synonyms/Aliases/Alternative Names of the Gene:

chemokine (C-X-C motif) ligand 5| chemokine (C-X-C motif) ligand 6 (granulocyte chemotactic protein 2)| C-X-C motif chemokine 5| C-X-C motif chemokine 6| cytokine LIX| GCP2| GCP-2| granulocyte chemotactic protein 2| SCYB6| small-inducible cytokine B5| small-inducible cytokine B6| Alveolar macrophage chemotactic factor 2| chemokine alpha 3| chemokine (C-X-C motif) ligand 6| CKA-3| CXC chemokine LIX| Cxcl5| D623_10008564| MDA_GLEAN10004386| PPBP| pro-platelet basic protein (chemokine (C-X-C motif) ligand 7)| small inducible cytokine subfamily B (Cys-X-Cys), member 6 (granulocyte chemotactic protein 2)| Small inducible cytokine subfamily B (Cys-X-Cys), member b| cxcl6

Policies

  • Terms of Service
  • Platform Consent
  • Privacy Policy
  • Disclaimer

About

  • Customer Support
  • Our Team
  • Affiliate Program

Navigation

  • Homepage
  • DNA Wellness Reports
  • Personalized Genetics Blog
  • Register your DNA Test Kit
  • Login
  • Careers
GET STARTED
  • SelfDecode is a personalized health report service, which enables users to obtain detailed information and reports based on their genome. SelfDecode does not treat, diagnose or cure any conditions, but is for informational and educational purposes alone.
SelfDecode © 2021 All Rights Reserved