Summary of CXCL5
This gene encodes a protein that is a chemokine. It promotes the formation of new blood vessels and helps remodel connective tissues. It might play a role in cancer cell proliferation, migration, and invasion (R).
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The Function of CXCL5
Involved in neutrophil activation. In vitro, ENA-78(8-78) and ENA-78(9-78) show a threefold higher chemotactic activity for neutrophil granulocytes.
Protein names
Recommended name:
C-X-C motif chemokine 5Short name:
8-78Alternative name(s):
ENA-78(1-78Epithelial-derived neutrophil-activating protein 78
Neutrophil-activating peptide ENA-78
Small-inducible cytokine B5
9-78
- RS2457996 (CXCL5) ??
- RS2472649 (CXCL5) ??
- RS425535 (CXCL5) ??
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Top Gene-Substance Interactions
CXCL5 Interacts with These Diseases
| Disease | Score |
Substances That Increase CXCL5
| Substances | Interaction | Organism | Category |
Substances That Decrease CXCL5
| Substances | Interaction | Organism | Category |
Conditions with Increased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Conditions with Decreased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Technical
The following transcription factors affect gene expression:
Gene Pathways:
Molecular Function:
Biological Processes:
- Cell-Cell Signaling
- Chemokine-Mediated Signaling Pathway
- Chemotaxis
- G-Protein Coupled Receptor Signaling Pathway
- Immune Response
- Inflammatory Response
- Neutrophil Mediated Immunity
- Positive Regulation Of Cell Proliferation
- Positive Regulation Of Leukocyte Chemotaxis
- Response To Lipopolysaccharide
- Signal Transduction