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  3. CTSZ

CTSZ (Cathepsin Z)

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The Function of CTSZ

Exhibits carboxy-monopeptidase as well as carboxy-dipeptidase activity.

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Protein names

Recommended name:

Cathepsin Z

Alternative name(s):

Cathepsin P
Cathepsin X

CTSZ SNPs

    To see your genotype, you should be logged in and have a file with your genotype uploaded.

  1. RS4812048 (CTSZ) ??

Top Gene-Substance Interactions

Substances That Increase CTSZ

Substances Interaction Organism Category

Substances That Decrease CTSZ

Substances Interaction Organism Category

Conditions with Increased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Conditions with Decreased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Technical

The following transcription factors affect gene expression:

  • PPAR-gamma1
  • PPAR-gamma2
  • PPAR-alpha
  • HNF-4alpha1
  • HNF-4alpha2
  • ITF-2
  • Tal-1beta
  • LyF-1
  • E47

Tissue specificity:

Widely expressed.

Gene Pathways:

  • Metabolism of proteins
  • Lysosome
  • Membrane Trafficking

Molecular Function:

  • Cysteine-Type Endopeptidase Activity
  • Cysteine-Type Peptidase Activity

Biological Processes:

  • Angiotensin Maturation
  • Copii Vesicle Coating
  • Epithelial Tube Branching Involved In Lung Morphogenesis
  • Er To Golgi Vesicle-Mediated Transport
  • Proteolysis
  • Proteolysis Involved In Cellular Protein Catabolic Process
*synonyms

Synonyms/Aliases/Alternative Names of the Gene:

hypothetical protein| cathepsin X| A306_08462| AS27_00620| AS28_06994| carboxypeptidase LB| cathepsin B2| cathepsin IV| cathepsin P| cathepsin Y| cathepsin Z1| cathepsin Z-like protein| cathepsin Z preproprotein| CATX| CB1_000308003| CTSX| cysteine-type carboxypeptidase| D2Wsu143e| D623_10023556| H920_07249| lysosomal carboxypeptidase B| M91_13648| M959_06520| MDA_GLEAN10010086| N300_15730| N301_06264| N302_00384| N303_11139| N305_13210| N306_01712| N307_09851| N308_00076| N309_11450| N310_10846| N312_04655| N320_00264| N321_07864| N322_06784| N324_07677| N325_09543| N326_09927| N328_09643| N330_14341| N331_07020| N332_10597| N333_12433| N334_04716| N335_11904| N339_10586| N340_10439| PAL_GLEAN10024593| PANDA_003571| preprocathepsin P| TREES_T100015640| Y1Q_005676| Y956_12332| Z169_02771| ctsz

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