The Function of CTF1
Induces cardiac myocyte hypertrophy in vitro. Binds to and activates the ILST/gp130 receptor.
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Protein names
Recommended name:
Cardiotrophin-1Short name:
CT-1- RS11649653 (CTF1) ??
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Top Gene-Substance Interactions
CTF1 Interacts with These Diseases
| Disease | Score |
Substances That Increase CTF1
| Substances | Interaction | Organism | Category |
Substances That Decrease CTF1
| Substances | Interaction | Organism | Category |
Conditions with Increased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Conditions with Decreased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Technical
The following transcription factors affect gene expression:
Tissue specificity:
Highly expressed in heart, skeletal muscle, prostate and ovary. Lower levels in lung, kidney, pancreas, thymus, testis and small intestine. Little or no expression in brain, placenta, liver, spleen, colon or peripheral blood leukocytes.
Gene Pathways:
Molecular Function:
Biological Processes:
- Cell Surface Receptor Signaling Pathway
- Cell-Cell Signaling
- Nervous System Development
- Muscle Organ Development
- Cell Proliferation
- Positive Regulation Of Cell Proliferation
- Positive Regulation Of Tyrosine Phosphorylation Of Stat3 Protein
- Neuron Development
- Leukemia Inhibitory Factor Signaling Pathway