Summary of CTBP2
This gene encodes 2 proteins, one is a transciption repressor and the other is part of specialized synapses (R).
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The Function of CTBP2
Isoform 2 probably acts as a scaffold for specialized synapses.
Protein names
Recommended name:
C-terminal-binding protein 2Alternative name(s):
CtBP2- RS10940579 (CTBP2) ??
- RS1915146 (CTBP2) ??
- RS3781426 (CTBP2) ??
- RS4962416 (CTBP2) ??
- RS718948 (CTBP2) ??
- RS9422860 (CTBP2) ??
- RS9649213 (CTBP2) ??
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Top Gene-Substance Interactions
CTBP2 Interacts with These Diseases
| Disease | Score |
Substances That Increase CTBP2
| Substances | Interaction | Organism | Category |
Substances That Decrease CTBP2
| Substances | Interaction | Organism | Category |
Conditions with Increased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Conditions with Decreased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Technical
The following transcription factors affect gene expression:
Tissue specificity:
Ubiquitous. Highest levels in heart, skeletal muscle, and pancreas.
Gene Pathways:
Molecular Function:
- Chromatin Binding
- Nad Binding
- Oxidoreductase Activity, Acting On The Ch-Oh Group Of Donors, Nad Or Nadp As Acceptor
- Protein Homodimerization Activity
- Transcription Coactivator Activity
- Transcription Corepressor Activity
Biological Processes:
- Negative Regulation Of Cell Proliferation
- Negative Regulation Of Transcription, Dna-Templated
- Negative Regulation Of Transcription From Rna Polymerase Ii Promoter
- Positive Regulation Of Chromatin Binding
- Positive Regulation Of Retinoic Acid Receptor Signaling Pathway
- Positive Regulation Of Transcription From Rna Polymerase Ii Promoter
- Transcription, Dna-Templated
- Viral Genome Replication
- White Fat Cell Differentiation