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  3. CTBP2

CTBP2 (C-terminal binding protein 2)

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Summary of CTBP2

This gene encodes 2 proteins, one is a transciption repressor and the other is part of specialized synapses (R). 

0 users want this gene increased, 0 users want it decreased

The Function of CTBP2

Isoform 2 probably acts as a scaffold for specialized synapses.

Protein names

Recommended name:

C-terminal-binding protein 2

Alternative name(s):

CtBP2

CTBP2 SNPs

    To see your genotype, you should be logged in and have a file with your genotype uploaded.

  1. RS10940579 (CTBP2) ??
  2. RS1915146 (CTBP2) ??
  3. RS3781426 (CTBP2) ??
  4. RS4962416 (CTBP2) ??
  5. RS718948 (CTBP2) ??
  6. RS9422860 (CTBP2) ??
  7. RS9649213 (CTBP2) ??

Top Gene-Substance Interactions

CTBP2 Interacts with These Diseases

Disease Score

Substances That Increase CTBP2

Substances Interaction Organism Category

Substances That Decrease CTBP2

Substances Interaction Organism Category

Conditions with Increased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Conditions with Decreased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Technical

The following transcription factors affect gene expression:

  • p300

Tissue specificity:

Ubiquitous. Highest levels in heart, skeletal muscle, and pancreas.

Gene Pathways:

  • Disease
  • Pathways in cancer
  • Signal Transduction
  • Wnt signaling pathway
  • Chronic myeloid leukemia
  • Notch signaling pathway

Molecular Function:

  • Chromatin Binding
  • Nad Binding
  • Oxidoreductase Activity, Acting On The Ch-Oh Group Of Donors, Nad Or Nadp As Acceptor
  • Protein Homodimerization Activity
  • Transcription Coactivator Activity
  • Transcription Corepressor Activity

Biological Processes:

  • Negative Regulation Of Cell Proliferation
  • Negative Regulation Of Transcription, Dna-Templated
  • Negative Regulation Of Transcription From Rna Polymerase Ii Promoter
  • Positive Regulation Of Chromatin Binding
  • Positive Regulation Of Retinoic Acid Receptor Signaling Pathway
  • Positive Regulation Of Transcription From Rna Polymerase Ii Promoter
  • Transcription, Dna-Templated
  • Viral Genome Replication
  • White Fat Cell Differentiation
*synonyms

Synonyms/Aliases/Alternative Names of the Gene:

hypothetical protein| Anapl_15380| AS27_02858| AS28_09691| CB1_001111020| ctbp| ctbp-b| C-terminal-binding protein 2| D623_10011605| D7Ertd45e| formin-like protein 7| gene trap ROSA b-geo 6| Gtrgeo6| H920_00380| M959_10823| MDA_GLEAN10021320| N300_07090| N301_09444| N302_12075| N303_10029| N305_01494| N306_04915| N307_11450| N308_02558| N309_01082| N310_00334| N312_02022| N321_05220| N324_02176| N327_11095| N328_03981| N330_05568| N332_02291| N335_11459| N336_02907| N340_12009| PAL_GLEAN10009004| PANDA_016334| Ribeye| TREES_T100012953| xctbp| Y1Q_029184| Y956_03034| Z169_09392| ctbp2

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