The Function of CST6
Shows moderate inhibition of cathepsin B but is not active against cathepsin C.
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Protein names
Recommended name:
Cystatin-MAlternative name(s):
Cystatin-6Cystatin-E
Top Gene-Substance Interactions
CST6 Interacts with These Diseases
| Disease | Score |
Substances That Increase CST6
| Substances | Interaction | Organism | Category |
Substances That Decrease CST6
| Substances | Interaction | Organism | Category |
Conditions with Increased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
|---|
Conditions with Decreased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
|---|
Technical
The following transcription factors affect gene expression:
Tissue specificity:
Restricted to the stratum granulosum of normal skin, the stratum granulosum/spinosum of psoriatic skin, and the secretory coils of eccrine sweat glands. Low expression levels are found in the nasal cavity.
Molecular Function:
Biological Processes:
- Epidermis Development
- Anatomical Structure Morphogenesis
- Negative Regulation Of Cysteine-Type Endopeptidase Activity