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  3. COL4A6

COL4A6 (Collagen type IV alpha 6 chain)

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The Function of COL4A6

Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen.

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Protein names

Recommended name:

Collagen alpha-6

Short name:

IV

COL4A6 SNPs

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  1. RS2295912 (COL4A6) ??

Top Gene-Substance Interactions

Substances That Increase COL4A6

Substances Interaction Organism Category

Substances That Decrease COL4A6

Substances Interaction Organism Category

Conditions with Increased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Conditions with Decreased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Technical

The following transcription factors affect gene expression:

  • Evi-1
  • Nkx5-1

Gene Pathways:

  • Pathways in cancer
  • Extracellular matrix organization
  • Small cell lung cancer
  • Amoebiasis
  • Protein digestion and absorption

Molecular Function:

  • Extracellular Matrix Structural Constituent

Biological Processes:

  • Cell Adhesion
  • Collagen Catabolic Process
  • Extracellular Matrix Organization
*synonyms

Synonyms/Aliases/Alternative Names of the Gene:

hypothetical protein| 60S ribosomal protein L21| alpha 6 chain collagen type IV| AS27_02099| AS28_02511| CB1_001991002| collagen alpha-6(IV) chain| collagen IV, alpha-6 polypeptide| collagen of basement membrane, alpha-6| collagen, type IV, alpha 6| CXDELq22.3| D623_10027017| DELXq22.3| DFNX6| dJ889N15.4 (Collagen Alpha 6(IV))| M91_04427| M959_08055| MDA_GLEAN10003846| N305_05464| N306_07083| N307_14364| N310_04506| N311_05104| N312_12290| N322_06657| N330_13472| N333_00952| N336_06812| N340_03140| PAL_GLEAN10003378| PANDA_015151| procollagen, type IV, alpha 6| TREES_T100020268| type IV alpha 6 collagen| type IV collagen alpha 6 chain| UY3_07390| Y1Q_031567| col4a6

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