The Function of CNN3
Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity.
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Protein names
Recommended name:
Calponin-3Alternative name(s):
Calponin, acidic isoform- RS860873 (CNN3) ??
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Top Gene-Substance Interactions
CNN3 Interacts with These Diseases
| Disease | Score |
Substances That Increase CNN3
| Substances | Interaction | Organism | Category |
Substances That Decrease CNN3
| Substances | Interaction | Organism | Category |
Conditions with Increased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
|---|
Conditions with Decreased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
|---|
Technical
The following transcription factors affect gene expression:
Tissue specificity:
Expressed in both non-smooth muscle tissues as well as smooth muscle tissues.
Molecular Function:
Biological Processes:
- Epithelial Cell Differentiation
- Actomyosin Structure Organization
- Negative Regulation Of Atpase Activity