The Function of CNEP1R1
Forms with the serine/threonine protein phosphatase CTDNEP1 an active complex which dephosphorylates and may activate LPIN1 and LPIN2. LPIN1 and LPIN2 are phosphatidate phosphatases that catalyze the conversion of phosphatidic acid to diacylglycerol and control the metabolism of fatty acids at differents levels. May indirectly modulate the lipid composition of nuclear and/or endoplasmic reticulum membranes and be required for proper nuclear membrane morphology and/or dynamics. May also indirectly regulate the production of lipid droplets and triacylglycerol.
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Protein names
Recommended name:
Nuclear envelope phosphatase-regulatory subunit 1Short name:
NEP1-R1Alternative name(s):
Transmembrane protein 188- RS12597023 (CNEP1R1) ??
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Top Gene-Substance Interactions
Substances That Increase CNEP1R1
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Substances That Decrease CNEP1R1
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Conditions with Increased Gene Activity
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Conditions with Decreased Gene Activity
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