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  3. CNEP1R1

CNEP1R1 (CTD nuclear envelope phosphatase 1 regulatory subunit 1)

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The Function of CNEP1R1

Forms with the serine/threonine protein phosphatase CTDNEP1 an active complex which dephosphorylates and may activate LPIN1 and LPIN2. LPIN1 and LPIN2 are phosphatidate phosphatases that catalyze the conversion of phosphatidic acid to diacylglycerol and control the metabolism of fatty acids at differents levels. May indirectly modulate the lipid composition of nuclear and/or endoplasmic reticulum membranes and be required for proper nuclear membrane morphology and/or dynamics. May also indirectly regulate the production of lipid droplets and triacylglycerol.

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Protein names

Recommended name:

Nuclear envelope phosphatase-regulatory subunit 1

Short name:

NEP1-R1

Alternative name(s):

Transmembrane protein 188

CNEP1R1 SNPs

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  1. RS12597023 (CNEP1R1) ??

Top Gene-Substance Interactions

Substances That Increase CNEP1R1

Substances Interaction Organism Category

Substances That Decrease CNEP1R1

Substances Interaction Organism Category

Conditions with Increased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Conditions with Decreased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

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