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  3. CKB

CKB (Creatine kinase B)

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The Function of CKB

Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa.

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Protein names

Recommended name:

Creatine kinase B-type

Short name:

B-CK

Alternative name(s):

Creatine kinase B chain

Top Gene-Substance Interactions

CKB Interacts with These Diseases

Disease Score

Substances That Increase CKB

Substances Interaction Organism Category

Substances That Decrease CKB

Substances Interaction Organism Category

Conditions with Increased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Conditions with Decreased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Technical

The following transcription factors affect gene expression:

  • ER-alpha
  • USF1
  • USF-1

Gene Pathways:

  • Metabolic pathways
  • Metabolism
  • Arginine and proline metabolism

Molecular Function:

  • Atp Binding
  • Creatine Kinase Activity
  • Ubiquitin Protein Ligase Binding

Biological Processes:

  • Cellular Chloride Ion Homeostasis
  • Creatine Metabolic Process
  • Substantia Nigra Development

Drug Bank:

  • Creatine
*synonyms

Synonyms/Aliases/Alternative Names of the Gene:

hypothetical protein| A306_03253| alternate protein| Anapl_17479| AS27_04641| AS28_02122| b-ck| BCK| B-creatine kinase| brain creatine kinase| CB1_000223009| Ck3| Ck-3| ckbb| Ckbr| creatine kinase| Creatine kinase B chain| creatine kinase B-like| creatine kinase brain| creatine kinase, brain| creatine kinase brain-type| creatine kinase B-type| creatine kinase, testis isozyme| D623_10007810| epididymis luminal protein 211| epididymis secretory protein Li 29| H920_16315| HEL-211| HEL-S-29| I79_004692| KCRT| M91_04951| M959_05716| MDA_GLEAN10005500| mumCK| N300_15832| N301_05476| N302_00159| N303_15472| N305_11581| N307_03850| N308_01618| N310_00152| N311_09697| N312_13308| N320_04676| N321_09534| N322_09019| N325_09136| N326_07736| N328_05850| N330_03713| N334_08235| N335_09383| N341_00201| PAL_GLEAN10020921| putative creatine kinase B variant 1| putative creatine kinase B variant 2| tck1| UY3_09975| XCK1| Y1Q_003296| Y956_11634| Z169_08146| ckb

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