• Navigation
  • Register My DNA Kit
  • Features
  • Pricing
  • FAQ
  • About
  • Labs
  • Login
  • Get started
  1. Home
  2. Genes
  3. CEBPB

CEBPB (CCAAT/enhancer binding protein beta)

Loading...

The Function of CEBPB

Isoform 3: Acts as a dominant negative through heterodimerization with isoform 2 (PubMed:11741938). Promotes osteoblast differentiation and osteoclastogenesis.

0 users want this gene increased, 0 users want it decreased

Protein names

Recommended name:

CCAAT/enhancer-binding protein beta

Short name:

LAP

Alternative name(s):

C/EBP beta
Liver activator protein
Liver-enriched inhibitory protein
LIP
Nuclear factor NF-IL6
Transcription factor 5
TCF-5

Top Gene-Substance Interactions

CEBPB Interacts with These Diseases

Disease Score

Substances That Increase CEBPB

Substances Interaction Organism Category

Substances That Decrease CEBPB

Substances Interaction Organism Category

Conditions with Increased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Conditions with Decreased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Technical

The following transcription factors affect gene expression:

  • GR
  • GR-alpha
  • GR-beta
  • CREB
  • AP-1
  • c-Jun
  • deltaCREB
  • C/EBPbeta

Tissue specificity:

Expressed at low levels in the lung, kidney and spleen.

Gene Pathways:

  • Cellular responses to stress
  • Mus musculus biological processes
  • Tuberculosis

Induction:

By ER stress.

Molecular Function:

  • Chromatin Binding
  • Dna Binding
  • Protein Heterodimerization Activity
  • Protein Homodimerization Activity
  • Rna Polymerase Ii Core Promoter Proximal Region Sequence-Specific Dna Binding
  • Rna Polymerase Ii Core Promoter Sequence-Specific Dna Binding
  • Rna Polymerase Ii Regulatory Region Sequence-Specific Dna Binding
  • Transcriptional Activator Activity, Rna Polymerase Ii Core Promoter Proximal Region Sequence-Specific Binding
  • Transcription Factor Activity, Rna Polymerase Ii Distal Enhancer Sequence-Specific Binding
  • Transcription Factor Activity, Sequence-Specific Dna Binding

Biological Processes:

  • Acute-Phase Response
  • Brown Fat Cell Differentiation
  • Cellular Response To Amino Acid Stimulus
  • Cellular Response To Interleukin-1
  • Cellular Response To Lipopolysaccharide
  • Cellular Response To Organic Cyclic Compound
  • Defense Response To Bacterium
  • Embryonic Placenta Development
  • Granuloma Formation
  • Hepatocyte Proliferation
  • Immune Response
  • Inflammatory Response
  • Intrinsic Apoptotic Signaling Pathway In Response To Endoplasmic Reticulum Stress
  • Liver Regeneration
  • Mammary Gland Epithelial Cell Differentiation
  • Mammary Gland Epithelial Cell Proliferation
  • Memory
  • Negative Regulation Of Neuron Apoptotic Process
  • Negative Regulation Of T Cell Proliferation
  • Negative Regulation Of Transcription, Dna-Templated
  • Neuron Differentiation
  • Ovarian Follicle Development
  • Positive Regulation Of Fat Cell Differentiation
  • Positive Regulation Of Interleukin-4 Production
  • Positive Regulation Of Osteoblast Differentiation
  • Positive Regulation Of Transcription From Rna Polymerase Ii Promoter
  • Positive Regulation Of Transcription From Rna Polymerase Ii Promoter In Response To Endoplasmic Reticulum Stress
  • Regulation Of Interleukin-6 Biosynthetic Process
  • Regulation Of Osteoclast Differentiation
  • Regulation Of Transcription, Dna-Templated
  • Regulation Of Transcription Involved In Cell Fate Commitment
  • Response To Endoplasmic Reticulum Stress
  • T-Helper 1 Cell Activation
  • Transcription From Rna Polymerase Ii Promoter
*synonyms

Synonyms/Aliases/Alternative Names of the Gene:

hypothetical protein| CCAAT/enhancer-binding protein beta| AGP/EBP| Anapl_00325| AS27_03239| AS28_06948| CCAAT box/enhancer binding protein beta| CCAAT/enhancer binding protein (C/EBP), beta| CCR protein| c/ebpb| cebpb-a| cebpb-b| c/ebp-beta| C/EBPbeta| C/EBP beta| CRP2| fe11e05| Il6dbp| IL-6DBP| interleukin-6-dependent-binding protein| interleukin 6-dependent DNA-binding protein| lap| LIP| liver-enriched transcriptional activator| nf-il6| Nfil6| NF-M| nuclear factor-IL6| nuclear factor NF-IL6| nuclear factor of interleukin 6| nuclear protein Il6| PAL_GLEAN10024474| PANDA_000797| SF-B| silencer factor B| tcf5| transcription factor 5| transcription factor C/EBP beta| transcription factor NF-M| UY3_06997| xC/EBPbeta| Y1Q_012128| cebpb

Policies

  • Terms of Service
  • Platform Consent
  • Privacy Policy
  • Disclaimer

About

  • Customer Support
  • Our Team
  • Affiliate Program

Navigation

  • Homepage
  • DNA Wellness Reports
  • Personalized Genetics Blog
  • Register your DNA Test Kit
  • Login
  • Careers
GET STARTED
  • SelfDecode is a personalized health report service, which enables users to obtain detailed information and reports based on their genome. SelfDecode does not treat, diagnose or cure any conditions, but is for informational and educational purposes alone.
SelfDecode © 2021 All Rights Reserved