The Function of CDS1
Provides CDP-diacylglycerol, an important precursor for the synthesis of phosphatidylinositol (PtdIns), phosphatidylglycerol, and cardiolipin. Overexpression may amplify cellular signaling responses from cytokines. May also play an important role in the signal transduction mechanism of retina and neural cells.
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Protein names
Recommended name:
Phosphatidate cytidylyltransferase 1Short name:
CDS 1Alternative name(s):
CDP-DAG synthase 1CDP-DG synthase 1
CDP-diacylglycerol synthase 1
CDP-diglyceride pyrophosphorylase 1
CDP-diglyceride synthase 1
CTP:phosphatidate cytidylyltransferase 1
- RS13152543 (CDS1) ??
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Top Gene-Substance Interactions
CDS1 Interacts with These Diseases
| Disease | Score |
Substances That Increase CDS1
| Substances | Interaction | Organism | Category |
Substances That Decrease CDS1
| Substances | Interaction | Organism | Category |
Conditions with Increased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Conditions with Decreased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Technical
The following transcription factors affect gene expression:
Tissue specificity:
Expressed in adult tissues such as placenta, brain, small intestine, ovary, testis and prostate. Highly expressed in fetal kidney, lung and brain. Lower level in fetal liver.
Gene Pathways:
Molecular Function:
Biological Processes:
- Cdp-Diacylglycerol Biosynthetic Process
- Phosphatidylglycerol Biosynthetic Process
- Phosphatidylinositol Biosynthetic Process
- Phototransduction
- Signal Transduction