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  3. CDS1

CDS1 (CDP-diacylglycerol synthase 1)

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The Function of CDS1

Provides CDP-diacylglycerol, an important precursor for the synthesis of phosphatidylinositol (PtdIns), phosphatidylglycerol, and cardiolipin. Overexpression may amplify cellular signaling responses from cytokines. May also play an important role in the signal transduction mechanism of retina and neural cells.

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Protein names

Recommended name:

Phosphatidate cytidylyltransferase 1

Short name:

CDS 1

Alternative name(s):

CDP-DAG synthase 1
CDP-DG synthase 1
CDP-diacylglycerol synthase 1
CDP-diglyceride pyrophosphorylase 1
CDP-diglyceride synthase 1
CTP:phosphatidate cytidylyltransferase 1

CDS1 SNPs

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  1. RS13152543 (CDS1) ??

Top Gene-Substance Interactions

CDS1 Interacts with These Diseases

Disease Score

Substances That Increase CDS1

Substances Interaction Organism Category

Substances That Decrease CDS1

Substances Interaction Organism Category

Conditions with Increased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Conditions with Decreased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Technical

The following transcription factors affect gene expression:

  • Evi-1
  • HNF-1A
  • CREB
  • c-Jun
  • deltaCREB
  • HNF-1
  • FOXI1

Tissue specificity:

Expressed in adult tissues such as placenta, brain, small intestine, ovary, testis and prostate. Highly expressed in fetal kidney, lung and brain. Lower level in fetal liver.

Gene Pathways:

  • Metabolic pathways
  • Metabolism
  • Phosphatidylinositol signaling system
  • Glycerophospholipid metabolism

Molecular Function:

  • Diacylglycerol Cholinephosphotransferase Activity
  • Phosphatidate Cytidylyltransferase Activity

Biological Processes:

  • Cdp-Diacylglycerol Biosynthetic Process
  • Phosphatidylglycerol Biosynthetic Process
  • Phosphatidylinositol Biosynthetic Process
  • Phototransduction
  • Signal Transduction
*synonyms

Synonyms/Aliases/Alternative Names of the Gene:

hypothetical protein| CDS| A306_08266| AS27_05739| AS28_03152| CDP-DAG synthase 1| CDP-DG synthase 1| CDP-DG synthetase 1| CDP-diacylglycerol synthase 1-like| CDP-diacylglycerol synthase (phosphatidate cytidylyltransferase) 1| CDP-diglyceride pyrophosphorylase 1| CDP-diglyceride synthase 1| CDP-diglyceride synthetase 1| CDS 1| CTP:phosphatidate cytidylyltransferase 1| D623_10021196| EGK_15712| GW7_21085| H920_03289| I79_018750| M959_05157| MDA_GLEAN10011403| N300_03074| N301_03947| N302_06077| N303_09492| N305_05249| N306_12656| N307_03751| N308_05694| N309_07859| N310_02055| N311_12830| N321_11103| N325_00476| N326_12248| N332_03730| N334_08616| N339_08717| N340_12465| PAL_GLEAN10012241| PANDA_001470| phosphatidate cytidylyltransferase 1| TREES_T100011600| UY3_12512| xcds1| Y1Q_024982| Y956_04673| Z169_13692| cds1

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