• Navigation
  • Register My DNA Kit
  • Features
  • Pricing
  • FAQ
  • About
  • Labs
  • Login
  • Get started
  1. Home
  2. Genes
  3. CDKN3

CDKN3 (Cyclin dependent kinase inhibitor 3)

Loading...

The Function of CDKN3

May play a role in cell cycle regulation. Dual specificity phosphatase active toward substrates containing either phosphotyrosine or phosphoserine residues. Dephosphorylates CDK2 at 'Thr-160' in a cyclin-dependent manner.

0 users want this gene increased, 0 users want it decreased

Protein names

Recommended name:

Cyclin-dependent kinase 3

Alternative name(s):

Cell division protein kinase 3

CDKN3 SNPs

    To see your genotype, you should be logged in and have a file with your genotype uploaded.

  1. RS2143963 (CDKN3) ??
  2. RS4251631 (CDKN3) ??
  3. RS4293296 (CDKN3) ??

Top Gene-Substance Interactions

Substances That Increase CDKN3

Substances Interaction Organism Category

Substances That Decrease CDKN3

Substances Interaction Organism Category

Conditions with Increased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Conditions with Decreased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Technical

The following transcription factors affect gene expression:

  • CUTL1
  • Nkx2-5

Induction:

Up-regulated in breast and prostate cancer cells.

Molecular Function:

  • Protein Serine/Threonine Phosphatase Activity
  • Protein Tyrosine/Serine/Threonine Phosphatase Activity
  • Protein Tyrosine Phosphatase Activity
  • Atp Binding
  • Cyclin-Dependent Protein Serine/Threonine Kinase Activity

Biological Processes:

  • Cell Cycle Arrest
  • G1/S Transition Of Mitotic Cell Cycle
  • Negative Regulation Of Cell Proliferation
  • Regulation Of Cyclin-Dependent Protein Serine/Threonine Kinase Activity
  • Cell Division
  • Cell Proliferation
  • Cellular Response To Dna Damage Stimulus
  • G0 To G1 Transition
  • Mitotic Nuclear Division
*synonyms

Synonyms/Aliases/Alternative Names of the Gene:

hypothetical protein| A306_10087| AS27_14304| AS28_07714| CDI1| CDK2-associated dual specificity phosphatase| CDK2-associated dual-specificity phosphatase| Cdk-associated protein phosphatase| CIP2| cyclin-dependent kinase inhibitor| cyclin-dependent kinase inhibitor 3| cyclin-dependent kinase inhibitor 3 (CDK2-associated dual specificity phosphatase)| cyclin-dependent kinase inhibitor 3-like protein| cyclin-dependent kinase interacting protein 2| cyclin-dependent kinase interactor 1| D623_10007591| EH28_23644| KAP| KAP1| kinase-associated phosphatase| M959_06444| MDA_GLEAN10023947| N300_01586| N301_11651| N302_06502| N303_03979| N305_09644| N306_05173| N307_08512| N310_04691| N311_09501| N312_08617| N320_05408| N322_00622| N324_07186| N325_02845| N326_01689| N327_10369| N328_04001| N329_10633| N330_03300| N331_00040| N332_07482| N333_03834| N334_04494| N335_09853| N336_06477| N339_09372| N340_05131| N341_00703| PAL_GLEAN10023290| PANDA_008341| Y956_12450| Z169_07170| cdkn3

Policies

  • Terms of Service
  • Platform Consent
  • Privacy Policy
  • Disclaimer

About

  • Customer Support
  • Our Team
  • Affiliate Program

Navigation

  • Homepage
  • DNA Wellness Reports
  • Personalized Genetics Blog
  • Register your DNA Test Kit
  • Login
  • Careers
GET STARTED
  • SelfDecode is a personalized health report service, which enables users to obtain detailed information and reports based on their genome. SelfDecode does not treat, diagnose or cure any conditions, but is for informational and educational purposes alone.
SelfDecode © 2021 All Rights Reserved