The Function of CDH3
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
0 users want this gene increased,
0 users want it decreased
Protein names
Recommended name:
Cadherin-3Alternative name(s):
Placental cadherinP-cadherin
- RS192253604 (CDH3) ??
- RS6499188 (CDH3) ??
To see your genotype, you should be logged in and have a file with your genotype uploaded.
Top Gene-Substance Interactions
Substances That Increase CDH3
| Substances | Interaction | Organism | Category |
Substances That Decrease CDH3
| Substances | Interaction | Organism | Category |
Conditions with Increased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
|---|
Conditions with Decreased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
|---|
Technical
The following transcription factors affect gene expression:
Tissue specificity:
Expressed in some normal epithelial tissues and in some carcinoma cell lines.
Gene Pathways:
Molecular Function:
Biological Processes:
- Adherens Junction Organization
- Canonical Wnt Signaling Pathway
- Cell Adhesion
- Hair Cycle Process
- Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules
- Keratinization
- Negative Regulation Of Catagen
- Negative Regulation Of Transforming Growth Factor Beta2 Production
- Positive Regulation Of Gene Expression
- Positive Regulation Of Insulin-Like Growth Factor Receptor Signaling Pathway
- Positive Regulation Of Keratinocyte Proliferation
- Positive Regulation Of Melanin Biosynthetic Process
- Positive Regulation Of Melanosome Transport
- Positive Regulation Of Monophenol Monooxygenase Activity
- Regulation Of Hair Cycle By Canonical Wnt Signaling Pathway
- Retina Homeostasis
- Single Organismal Cell-Cell Adhesion
- Visual Perception
- Wound Healing