The Function of CDA
This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.
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Protein names
Recommended name:
Cytidine deaminaseAlternative name(s):
Cytidine aminohydrolase- RS1048977 (CDA) ??
- RS10916814 (CDA) ??
- RS2072671 (CDA) ??
- RS532545 (CDA) ??
- RS60369023 (CDA) ??
- RS690140 (CDA) ??
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Top Gene-Substance Interactions
Substances That Increase CDA
| Substances | Interaction | Organism | Category |
Substances That Decrease CDA
| Substances | Interaction | Organism | Category |
Conditions with Increased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Conditions with Decreased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Technical
The following transcription factors affect gene expression:
Tissue specificity:
Highly expressed in granulocytes while expression is very low in fibroblasts, chondrocytes, monocytes, and T- as well as B-cell lines.
Molecular Function:
Biological Processes:
- Cell Surface Receptor Signaling Pathway
- Cytidine Deamination
- Cytosine Metabolic Process
- Negative Regulation Of Cell Growth
- Negative Regulation Of Nucleotide Metabolic Process
- Protein Homotetramerization
- Pyrimidine-Containing Compound Salvage
- Pyrimidine Nucleoside Salvage