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  3. CDA

CDA (Cytidine deaminase)

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The Function of CDA

This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.

0 users want this gene increased, 0 users want it decreased

Protein names

Recommended name:

Cytidine deaminase

Alternative name(s):

Cytidine aminohydrolase

CDA SNPs

    To see your genotype, you should be logged in and have a file with your genotype uploaded.

  1. RS1048977 (CDA) ??
  2. RS10916814 (CDA) ??
  3. RS2072671 (CDA) ??
  4. RS532545 (CDA) ??
  5. RS60369023 (CDA) ??
  6. RS690140 (CDA) ??

Top Gene-Substance Interactions

Substances That Increase CDA

Substances Interaction Organism Category

Substances That Decrease CDA

Substances Interaction Organism Category

Conditions with Increased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Conditions with Decreased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Technical

The following transcription factors affect gene expression:

  • NF-kappaB
  • AP-1
  • c-Jun
  • NF-kappaB1
  • PPAR-alpha

Tissue specificity:

Highly expressed in granulocytes while expression is very low in fibroblasts, chondrocytes, monocytes, and T- as well as B-cell lines.

Gene Pathways:

  • Metabolic pathways
  • Metabolism
  • Pyrimidine metabolism
  • Drug metabolism - other enzymes

Molecular Function:

  • Cytidine Deaminase Activity
  • Nucleoside Binding
  • Protein Homodimerization Activity
  • Zinc Ion Binding

Biological Processes:

  • Cell Surface Receptor Signaling Pathway
  • Cytidine Deamination
  • Cytosine Metabolic Process
  • Negative Regulation Of Cell Growth
  • Negative Regulation Of Nucleotide Metabolic Process
  • Protein Homotetramerization
  • Pyrimidine-Containing Compound Salvage
  • Pyrimidine Nucleoside Salvage

Drug Bank:

  • Cytarabine
  • Gemcitabine
  • Azacitidine
  • Capecitabine
*synonyms

Synonyms/Aliases/Alternative Names of the Gene:

A306_07038| CDD| cytidine aminohydrolase| cytidine deaminase-like protein| cytosine nucleoside deaminase| GW7_01843| H920_06032| M959_03268| N301_15776| N302_12231| N303_02627| N307_01400| N309_01727| N310_00579| N320_10610| N321_11974| N322_05728| N324_08160| N325_10317| N326_10065| N331_02777| N332_09167| N333_07601| N336_10240| N339_12834| N341_09966| PAL_GLEAN10015206| small cytidine deaminase| TREES_T100008785| Y1Q_013712| Y956_03101| Z169_14455| cda

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