The Function of CD9
Involved in platelet activation and aggregation. Regulates paranodal junction formation. Involved in cell adhesion, cell motility and tumor metastasis. Required for sperm-egg fusion.
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Protein names
Recommended name:
CD9 antigenAlternative name(s):
5H9 antigenCell growth-inhibiting gene 2 protein
Leukocyte antigen MIC3
Motility-related protein
MRP-1
Tetraspanin-29
Tspan-29
p24
CD antigen CD9
- RS3181157 (CD9) ??
- RS7342306 (CD9) ??
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Top Gene-Substance Interactions
CD9 Interacts with These Diseases
| Disease | Score |
Substances That Increase CD9
| Substances | Interaction | Organism | Category |
Substances That Decrease CD9
| Substances | Interaction | Organism | Category |
Conditions with Increased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
|---|
Conditions with Decreased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Technical
The following transcription factors affect gene expression:
Tissue specificity:
Detected in platelets (at protein level). Expressed by a variety of hematopoietic and epithelial cells.
Gene Pathways:
Biological Processes:
- Platelet Degranulation
- Movement Of Cell Or Subcellular Component
- Cell Adhesion
- Cell Surface Receptor Signaling Pathway
- Fusion Of Sperm To Egg Plasma Membrane
- Brain Development
- Negative Regulation Of Cell Proliferation
- Response To Water Deprivation
- Oligodendrocyte Development
- Platelet Activation
- Paranodal Junction Assembly
- Receptor Internalization
- Cellular Response To Low-Density Lipoprotein Particle Stimulus