• Navigation
  • Register My DNA Kit
  • Features
  • Pricing
  • FAQ
  • About
  • Labs
  • Login
  • Get started
  1. Home
  2. Genes
  3. CD86

CD86 (CD86 molecule)

Loading...

Summary of CD86

This gene encodes a protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells and helps activate the T-cell (R). 

0 users want this gene increased, 0 users want it decreased

The Function of CD86

(Microbial infection) Acts as a receptor for adenovirus subgroup B.

Protein names

Recommended name:

T-lymphocyte activation antigen CD86

Short name:

B70

Alternative name(s):

Activation B7-2 antigen
BU63
CTLA-4 counter-receptor B7.2
FUN-1
CD antigen CD86

CD86 SNPs

    To see your genotype, you should be logged in and have a file with your genotype uploaded.

  1. RS1129055 (CD86) ??
  2. RS17281995 (CD86) ??
  3. RS2681411 (CD86) ??
  4. RS2681416 (CD86) ??
  5. RS4308217 (CD86) ??
  6. RS9282641 (CD86) ??

Top Gene-Substance Interactions

CD86 Interacts with These Diseases

Disease Score

Substances That Increase CD86

Substances Interaction Organism Category

Substances That Decrease CD86

Substances Interaction Organism Category

Conditions with Increased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Conditions with Decreased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Technical

The following transcription factors affect gene expression:

  • NF-kappaB
  • CREB
  • deltaCREB
  • NF-kappaB1
  • STAT1
  • STAT1beta
  • STAT1alpha

Tissue specificity:

Expressed by activated B-lymphocytes and monocytes.

Gene Pathways:

  • Disease
  • Immune System
  • Signal Transduction
  • Autoimmune thyroid disease
  • Toll-like receptor signaling pathway
  • Cell adhesion molecules (CAMs)
  • Allograft rejection
  • Graft-versus-host disease
  • Intestinal immune network for IgA production
  • Rheumatoid arthritis
  • Type I diabetes mellitus
  • Systemic lupus erythematosus
  • Viral myocarditis

Molecular Function:

  • Coreceptor Activity
  • Phosphatidylinositol-4,5-Bisphosphate 3-Kinase Activity
  • Receptor Activity
  • Virus Receptor Activity

Biological Processes:

  • Adaptive Immune Response
  • Aging
  • B Cell Activation
  • Cell-Cell Signaling
  • Cellular Response To Cytokine Stimulus
  • Cellular Response To Lipopolysaccharide
  • Cellular Response To Metal Ion
  • Defense Response To Virus
  • Immune Response
  • Myeloid Dendritic Cell Differentiation
  • Negative Regulation Of T Cell Anergy
  • Phosphatidylinositol-Mediated Signaling
  • Positive Regulation Of Activated T Cell Proliferation
  • Positive Regulation Of Cell Proliferation
  • Positive Regulation Of Interleukin-2 Biosynthetic Process
  • Positive Regulation Of Interleukin-4 Biosynthetic Process
  • Positive Regulation Of Lymphotoxin A Biosynthetic Process
  • Positive Regulation Of T-Helper 2 Cell Differentiation
  • Positive Regulation Of Transcription, Dna-Templated
  • Regulation Of Phosphatidylinositol 3-Kinase Signaling
  • Response To Interferon-Gamma
  • Response To Yeast
  • T Cell Activation
  • T Cell Costimulation
  • T Cell Proliferation Involved In Immune Response
  • Toll-Like Receptor 3 Signaling Pathway

Drug Bank:

  • Abatacept
  • Anti-Thymocyte Globulin (Rabbit)
  • Belatacept
*synonyms

Synonyms/Aliases/Alternative Names of the Gene:

hypothetical protein| costimulatory molecule| B7| A306_05211| activation B7-2 antigen| AS27_05460| AS28_01436| B70| B7-1 costimulatory molecule| B7-2| B7.2| B7-2 protein| B-lymphocyte activation antigen B7-2| BU63| CB1_001278029| Cd28l2| CD28LG2| CD80/86| CD80/86 molecule| cd86 antigen| CD86 antigen (CD28 antigen ligand 2, B7-2 antigen)| CD86/B7-2 costimulatory molecule| CD86 membrane protein long isoform| CLS1| costimulatory B-lymphocyte antigen B7-2| co-stimulatory molecule B7-2| CTLA-4 counter-receptor B7.2| early T cell costimulatory molecule-1| ETC-1| FUN-1| GW7_11053| H920_07809| I79_007451| LAB72| Ly58| Ly-58| M91_16648| M959_00371| MB7| MB7-2| MDA_GLEAN10018578| membrane glycoprotein| N300_13285| N301_07508| N302_08087| N305_06314| N306_11726| N307_04985| N308_11172| N311_11819| N321_04470| N325_06403| N331_11302| N335_00855| PANDA_017028| T-lymphocyte activation antigen CD86| TREES_T100010200| TS/A-2| Y1Q_002753| Y956_11510| Z169_15798| cd86

Policies

  • Terms of Service
  • Platform Consent
  • Privacy Policy
  • Disclaimer

About

  • Customer Support
  • Our Team
  • Affiliate Program

Navigation

  • Homepage
  • DNA Wellness Reports
  • Personalized Genetics Blog
  • Register your DNA Test Kit
  • Login
  • Careers
GET STARTED
  • SelfDecode is a personalized health report service, which enables users to obtain detailed information and reports based on their genome. SelfDecode does not treat, diagnose or cure any conditions, but is for informational and educational purposes alone.
SelfDecode © 2021 All Rights Reserved