The Function of CD69
Involved in lymphocyte proliferation and functions as a signal transmitting receptor in lymphocytes, natural killer (NK) cells, and platelets.
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Protein names
Recommended name:
Early activation antigen CD69Short name:
AIMAlternative name(s):
Activation inducer moleculeBL-AC/P26
C-type lectin domain family 2 member C
EA1
Early T-cell activation antigen p60
GP32/28
Leukocyte surface antigen Leu-23
MLR-3
CD antigen CD69
- RS4763879 (CD69) ??
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Top Gene-Substance Interactions
CD69 Interacts with These Diseases
| Disease | Score |
Substances That Increase CD69
| Substances | Interaction | Organism | Category |
Substances That Decrease CD69
| Substances | Interaction | Organism | Category |
Conditions with Increased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Conditions with Decreased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Technical
The following transcription factors affect gene expression:
Tissue specificity:
Expressed on the surface of activated T-cells, B-cells, natural killer cells, neutrophils, eosinophils, epidermal Langerhans cells and platelets.
Induction:
By antigens, mitogens or activators of PKC on the surface of T and B-lymphocytes. By interaction of IL-2 with the p75 IL-2R on the surface of NK cells.
Developmental stage:
Earliest inducible cell surface glycoprotein acquired during lymphoid activation.