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  3. CD69

CD69 (CD69 molecule)

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The Function of CD69

Involved in lymphocyte proliferation and functions as a signal transmitting receptor in lymphocytes, natural killer (NK) cells, and platelets.

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Protein names

Recommended name:

Early activation antigen CD69

Short name:

AIM

Alternative name(s):

Activation inducer molecule
BL-AC/P26
C-type lectin domain family 2 member C
EA1
Early T-cell activation antigen p60
GP32/28
Leukocyte surface antigen Leu-23
MLR-3
CD antigen CD69

CD69 SNPs

    To see your genotype, you should be logged in and have a file with your genotype uploaded.

  1. RS4763879 (CD69) ??

Top Gene-Substance Interactions

CD69 Interacts with These Diseases

Disease Score

Substances That Increase CD69

Substances Interaction Organism Category

Substances That Decrease CD69

Substances Interaction Organism Category

Conditions with Increased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Conditions with Decreased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Technical

The following transcription factors affect gene expression:

  • NF-kappaB
  • PPAR-gamma1
  • PPAR-gamma2
  • GR
  • CREB
  • AP-1
  • c-Jun
  • deltaCREB
  • NF-kappaB1

Tissue specificity:

Expressed on the surface of activated T-cells, B-cells, natural killer cells, neutrophils, eosinophils, epidermal Langerhans cells and platelets.

Induction:

By antigens, mitogens or activators of PKC on the surface of T and B-lymphocytes. By interaction of IL-2 with the p75 IL-2R on the surface of NK cells.

Developmental stage:

Earliest inducible cell surface glycoprotein acquired during lymphoid activation.

Molecular Function:

  • Calcium Ion Binding
  • Carbohydrate Binding
  • Transmembrane Signaling Receptor Activity
*synonyms

Synonyms/Aliases/Alternative Names of the Gene:

hypothetical protein| activation inducer molecule (AIM/CD69)| AIM| BL-AC/P26| CD69 antigen| CD69 antigen (p60| CD69 antigen (p60, early T-cell activation antigen)| CLEC2C| C-type lectin domain family 2 member A| C-type lectin domain family 2, member C| C-type lectin-like receptor| EA1| Early activation antigen CD69| early activation antigen CD69-like| early lymphocyte activation antigen| early T-cell activation antigen)| early T-cell activation antigen p60| EGK_03348| GP32/28| leukocyte surface antigen Leu-23| M91_10227| MLR-3| p60| PANDA_014862| TREES_T100020242| type II membrane protein CD69| VEA| Very Early Activation Antigen| cd69

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