The Function of CCK
This peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear. Binding to CCK-A receptors stimulates amylase release from the pancreas, binding to CCK-B receptors stimulates gastric acid secretion.
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Protein names
Recommended name:
CholecystokininShort name:
CCKAlternative name(s):
CCK58(1-49
CCK39
CCK33
CCK25
CCK18
CCK12
CCK8
CCK7
CCK5
- RS1799923 (CCK) ??
- RS4377469 (CCK) ??
- RS8192472 (CCK) ??
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Top Gene-Substance Interactions
CCK Interacts with These Diseases
| Disease | Score |
Substances That Increase CCK
| Substances | Interaction | Organism | Category |
Substances That Decrease CCK
| Substances | Interaction | Organism | Category |
Conditions with Increased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Conditions with Decreased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Technical
The following transcription factors affect gene expression:
Molecular Function:
Biological Processes:
- Activation Of Cysteine-Type Endopeptidase Activity Involved In Apoptotic Process
- Axonogenesis
- Behavioral Fear Response
- Eating Behavior
- Negative Regulation Of Appetite
- Neuron Migration
- Positive Regulation Of Cell Proliferation
- Positive Regulation Of Glutamate Secretion
- Positive Regulation Of Mitochondrial Depolarization
- Positive Regulation Of Peptidyl-Tyrosine Phosphorylation
- Positive Regulation Of Protein Oligomerization
- Protein Kinase C-Activating G-Protein Coupled Receptor Signaling Pathway
- Regulation Of Sensory Perception Of Pain
- Release Of Cytochrome C From Mitochondria
- Signal Transduction