The Function of CCK
This peptide hormone induces gall bladder contraction and the release of pancreatic enzymes in the gut. Its function in the brain is not clear. Binding to CCK-A receptors stimulates amylase release from the pancreas, binding to CCK-B receptors stimulates gastric acid secretion.
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Protein names
Recommended name:
CholecystokininShort name:
CCKAlternative name(s):
CCK58(1-49
CCK39
CCK33
CCK25
CCK18
CCK12
CCK8
CCK7
CCK5
- RS1799923 (CCK) ??
- RS4377469 (CCK) ??
- RS8192472 (CCK) ??
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Top Gene-Substance Interactions
CCK Interacts with These Diseases
| Disease | Score |
Substances That Increase CCK
| Substances | Interaction | Organism | Category |
Substances That Decrease CCK
| Substances | Interaction | Organism | Category |
Conditions with Increased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Conditions with Decreased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Technical
The following transcription factors affect gene expression:
Molecular Function:
Biological Processes:
- Behavioral Fear Response
- Neuron Migration
- Release Of Cytochrome C From Mitochondria
- Activation Of Cysteine-Type Endopeptidase Activity Involved In Apoptotic Process
- Signal Transduction
- Protein Kinase C-Activating G-Protein Coupled Receptor Signaling Pathway
- Axonogenesis
- Positive Regulation Of Cell Proliferation
- Positive Regulation Of Glutamate Secretion
- Negative Regulation Of Appetite
- Positive Regulation Of Protein Oligomerization
- Eating Behavior
- Positive Regulation Of Peptidyl-Tyrosine Phosphorylation
- Positive Regulation Of Mitochondrial Depolarization
- Regulation Of Sensory Perception Of Pain