The Function of CAPZB
F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. Plays a role in the regulation of cell morphology and cytoskeletal organization.
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Protein names
Recommended name:
F-actin-capping protein subunit betaAlternative name(s):
CapZ beta- RS12045440 (CAPZB) ??
- RS12136530 (CAPZB) ??
- RS7667 (CAPZB) ??
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Top Gene-Substance Interactions
CAPZB Interacts with These Diseases
| Disease | Score |
Substances That Increase CAPZB
| Substances | Interaction | Organism | Category |
Substances That Decrease CAPZB
| Substances | Interaction | Organism | Category |
Conditions with Increased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
|---|
Conditions with Decreased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Technical
The following transcription factors affect gene expression:
Gene Pathways:
Molecular Function:
Biological Processes:
- Movement Of Cell Or Subcellular Component
- Cytoskeleton Organization
- Blood Coagulation
- Regulation Of Lamellipodium Assembly
- Regulation Of Cell Morphogenesis
- Actin Cytoskeleton Organization
- Barbed-End Actin Filament Capping
- Negative Regulation Of Filopodium Assembly