The Function of CAPZA1
F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
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Protein names
Recommended name:
F-actin-capping protein subunit alpha-1Alternative name(s):
CapZ alpha-1- RS10745332 (CAPZA1) ??
- RS12120956 (CAPZA1) ??
- RS17030613 (CAPZA1) ??
- RS2932538 (CAPZA1) ??
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Top Gene-Substance Interactions
Substances That Increase CAPZA1
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Substances That Decrease CAPZA1
| Substances | Interaction | Organism | Category |
Conditions with Increased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Conditions with Decreased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Technical
The following transcription factors affect gene expression:
Gene Pathways:
Molecular Function:
Biological Processes:
- Barbed-End Actin Filament Capping
- Blood Coagulation
- Innate Immune Response
- Movement Of Cell Or Subcellular Component
- Protein Complex Assembly