The Function of CA3
Reversible hydration of carbon dioxide.
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Protein names
Recommended name:
Carbonic anhydrase 3Short name:
CA-IIIAlternative name(s):
Carbonate dehydratase IIICarbonic anhydrase III
Top Gene-Substance Interactions
CA3 Interacts with These Diseases
| Disease | Score |
Substances That Increase CA3
| Substances | Interaction | Organism | Category |
Substances That Decrease CA3
| Substances | Interaction | Organism | Category |
Conditions with Increased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
|---|
Conditions with Decreased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Technical
The following transcription factors affect gene expression:
Tissue specificity:
Muscle specific.
Gene Pathways:
Developmental stage:
At 6 weeks gestation, transcripts accumulate at low levels in the somites and at high levels throughout the notochord. As gestation continues, CA3 becomes abundant in all developing muscle masses and continues at high to moderate levels in the notochord.
Enzyme Regulation:
Activated by proton donors such as imidazole and the dipeptide histidylhistidine. Inhibited by coumarins and sulfonamide derivatives such as acetazolamide.