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  3. C12ORF5

C12ORF5 (Chromosome 12 open reading frame 57 L homeolog)

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Protein names

Recommended name:

Fructose-2,6-bisphosphatase TIGAR

Alternative name(s):

TP53-induced glycolysis and apoptosis regulator
TP53-induced glycolysis regulatory phosphatase

C12ORF5 SNPs

    To see your genotype, you should be logged in and have a file with your genotype uploaded.

  1. RS10849033 (C12ORF5) ??
  2. RS4625554 (C12ORF5) ??

Conditions with Decreased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Technical

The following transcription factors affect gene expression:

  • ER-alpha
  • PPAR-gamma1
  • PPAR-gamma2
  • TBP
  • ITF-2
  • Tal-1beta
  • Lmo2

Molecular Function:

  • Bisphosphoglycerate 2-Phosphatase Activity
  • Fructose-2,6-Bisphosphate 2-Phosphatase Activity

Biological Processes:

  • Apoptotic Process
  • Autophagy
  • Cellular Response To Cobalt Ion
  • Cellular Response To Dna Damage Stimulus
  • Cellular Response To Hypoxia
  • Fructose 1,6-Bisphosphate Metabolic Process
  • Fructose 2,6-Bisphosphate Metabolic Process
  • Intestinal Epithelial Cell Development
  • Negative Regulation Of Glucose Catabolic Process To Lactate Via Pyruvate
  • Negative Regulation Of Glycolytic Process
  • Negative Regulation Of Macromitophagy
  • Negative Regulation Of Neuron Death
  • Negative Regulation Of Programmed Cell Death
  • Negative Regulation Of Reactive Oxygen Species Metabolic Process
  • Positive Regulation Of Cardiac Muscle Cell Apoptotic Process
  • Positive Regulation Of Dna Repair
  • Positive Regulation Of Hexokinase Activity
  • Regulation Of Pentose-Phosphate Shunt
  • Regulation Of Response To Dna Damage Checkpoint Signaling
  • Response To Gamma Radiation
  • Response To Ischemia
  • Response To Xenobiotic Stimulus
*synonyms

Synonyms/Aliases/Alternative Names of the Gene:

hypothetical protein| c12orf57| protein C10| XELAEV_18034338mg| c12orf5

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