The Function of BMF
May play a role in apoptosis. Isoform 1 seems to be the main initiator.
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Protein names
Recommended name:
Bcl-2-modifying factor- RS8023845 (BMF) ??
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Top Gene-Substance Interactions
Substances That Increase BMF
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Substances That Decrease BMF
| Substances | Interaction | Organism | Category |
Conditions with Increased Gene Activity
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Conditions with Decreased Gene Activity
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Technical
The following transcription factors affect gene expression:
Tissue specificity:
Isoform 1 is mainly expressed in B-lymphoid cells. Isoform 2 and isoform 3 are mainly expressed in B-CLL and normal B-cells.
Gene Pathways:
Biological Processes:
- Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway
- Positive Regulation Of Protein Homooligomerization
- Positive Regulation Of Apoptotic Process
- Anoikis
- Positive Regulation Of Release Of Cytochrome C From Mitochondria
- Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway
- Positive Regulation Of Intrinsic Apoptotic Signaling Pathway