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  3. BMF

BMF (Bcl2 modifying factor)

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The Function of BMF

May play a role in apoptosis. Isoform 1 seems to be the main initiator.

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Protein names

Recommended name:

Bcl-2-modifying factor

BMF SNPs

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  1. RS8023845 (BMF) ??

Top Gene-Substance Interactions

Substances That Increase BMF

Substances Interaction Organism Category

Substances That Decrease BMF

Substances Interaction Organism Category

Conditions with Increased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Conditions with Decreased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Technical

The following transcription factors affect gene expression:

  • NF-kappaB
  • AhR
  • Arnt
  • NF-kappaB1
  • SREBP-1a
  • SREBP-1c
  • SREBP-1b
  • NF-kappaB2

Tissue specificity:

Isoform 1 is mainly expressed in B-lymphoid cells. Isoform 2 and isoform 3 are mainly expressed in B-CLL and normal B-cells.

Gene Pathways:

  • Apoptosis

Biological Processes:

  • Anoikis
  • Positive Regulation Of Apoptotic Process
  • Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
  • Positive Regulation Of Protein Homooligomerization
  • Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway
  • Positive Regulation Of Release Of Cytochrome C From Mitochondria
  • Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway
*synonyms

Synonyms/Aliases/Alternative Names of the Gene:

hypothetical protein| A306_08031| Anapl_04408| AS27_09346| AS28_07377| Bcl-2 modifying factor| Bcl-2-modifying factor| bcl-2-modifying factor isoform bmf-1| bcl-2-modifying factor isoform bmf-3| bcl-2-modifying factor-like protein| CB1_000277007| EH28_01563| H920_05543| I79_010202| M959_13274| N300_01987| N301_08584| N302_01693| N303_07110| N305_09592| N306_10787| N307_10062| N308_04680| N309_05645| N310_02802| N311_00294| N312_00260| N320_10593| N324_07495| N325_09883| N326_10106| N327_07838| N328_10656| N329_07778| N330_00435| N332_10081| N333_00330| N334_00557| N335_06166| N339_00215| PAL_GLEAN10023628| PANDA_001082| UY3_16182| Y1Q_018796| Y956_16533| Z169_03953| bmf

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