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  3. BACH2

BACH2 (BTB domain and CNC homolog 2)

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Summary of BACH2

The BACH2 gene encodes a protein that acts as repressor or activato. It plays important roles in coordinating transcription activation and repression by MAFK and induces cell death in response to oxidative stress (R). 

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The Function of BACH2

Transcriptional regulator that acts as repressor or activator. Binds to Maf recognition elements (MARE). Play important roles in coordinating transcription activation and repression by MAFK (By similarity). Induces apoptosis in response to oxidative stress through repression of the antiapoptotic factor HMOX1.

Protein names

Recommended name:

Transcription regulator protein BACH2

Alternative name(s):

BTB and CNC homolog 2

BACH2 SNPs

    To see your genotype, you should be logged in and have a file with your genotype uploaded.

  1. RS10806425 (BACH2) ??
  2. RS10944479 (BACH2) ??
  3. RS11755527 (BACH2) ??
  4. RS12204127 (BACH2) ??
  5. RS12212193 (BACH2) ??
  6. RS12529935 (BACH2) ??
  7. RS1847472 (BACH2) ??
  8. RS2289577 (BACH2) ??
  9. RS2474619 (BACH2) ??
  10. RS370409 (BACH2) ??
  11. RS3757247 (BACH2) ??
  12. RS404256 (BACH2) ??
  13. RS6917758 (BACH2) ??

Top Gene-Substance Interactions

Substances That Increase BACH2

Substances Interaction Organism Category

Substances That Decrease BACH2

Substances Interaction Organism Category

Conditions with Increased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Conditions with Decreased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Technical

The following transcription factors affect gene expression:

  • AP-1
  • c-Jun

Tissue specificity:

B-cell specific.

Molecular Function:

  • Rna Polymerase Ii Distal Enhancer Sequence-Specific Dna Binding
  • Transcriptional Repressor Activity, Rna Polymerase Ii Distal Enhancer Sequence-Specific Binding
  • Transcription Factor Activity, Sequence-Specific Dna Binding

Biological Processes:

  • Protein Ubiquitination
  • Single-Organism Nuclear Import
  • Transcription From Rna Polymerase Ii Promoter
*synonyms

Synonyms/Aliases/Alternative Names of the Gene:

hypothetical protein| A306_16176| Anapl_09380| AS27_04981| AS28_10071| BTB and CNC homolog 2| BTB and CNC homology 1, basic leucine zipper transcription facto| BTB and CNC homology 1, basic leucine zipper transcription factor 2| BTB and CNC homology 2| BTB and CNC homology, basic leucine zipper transcription factor 2| BTB and CNC-like protein 2| BTB and CNC-like proteiny 1, basic leucine zipper transcription factor 2| BTBD25| CB1_000371003| D623_10023882| EGK_15169| GW7_21221| H920_09183| M91_21520| N300_01162| N301_04236| N302_15591| N303_00283| N306_11786| N307_06313| N309_15054| N312_12567| N320_02542| N321_10716| N322_10547| N324_08521| N325_01813| N326_10621| N327_13435| N329_07672| N330_12030| N332_00603| N333_12747| N334_07268| N335_02849| N336_03526| N339_08762| N340_07775| N341_06653| PAL_GLEAN10025165| PANDA_014576| RGD1562865| Transcription regulator protein BACH2| Transcription regulator protein BACH2 (BTB and CNC homolog 2)| transcription regulator protein BACH2-like protein| TREES_T100021644| UY3_10092| Y1Q_002603| Y956_07831| Z169_05057| bach2

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