Summary of BACH2
The BACH2 gene encodes a protein that acts as repressor or activato. It plays important roles in coordinating transcription activation and repression by MAFK and induces cell death in response to oxidative stress (R).
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The Function of BACH2
Transcriptional regulator that acts as repressor or activator. Binds to Maf recognition elements (MARE). Play important roles in coordinating transcription activation and repression by MAFK (By similarity). Induces apoptosis in response to oxidative stress through repression of the antiapoptotic factor HMOX1.
Protein names
Recommended name:
Transcription regulator protein BACH2Alternative name(s):
BTB and CNC homolog 2- RS10806425 (BACH2) ??
- RS10944479 (BACH2) ??
- RS11755527 (BACH2) ??
- RS12204127 (BACH2) ??
- RS12212193 (BACH2) ??
- RS12529935 (BACH2) ??
- RS1847472 (BACH2) ??
- RS2289577 (BACH2) ??
- RS2474619 (BACH2) ??
- RS370409 (BACH2) ??
- RS3757247 (BACH2) ??
- RS404256 (BACH2) ??
- RS6917758 (BACH2) ??
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Top Gene-Substance Interactions
Substances That Increase BACH2
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Substances That Decrease BACH2
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Conditions with Increased Gene Activity
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Conditions with Decreased Gene Activity
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Technical
The following transcription factors affect gene expression:
Tissue specificity:
B-cell specific.
Molecular Function:
- Rna Polymerase Ii Distal Enhancer Sequence-Specific Dna Binding
- Transcriptional Repressor Activity, Rna Polymerase Ii Distal Enhancer Sequence-Specific Binding
- Transcription Factor Activity, Sequence-Specific Dna Binding