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  3. B4GALT4

B4GALT4 (Beta-1,4-galactosyltransferase 4)

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The Function of B4GALT4

Responsible for the synthesis of complex-type N-linked oligosaccharides in many glycoproteins as well as the carbohydrate moieties of glycolipids.

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Protein names

Recommended name:

Beta-1,4-galactosyltransferase 4

Alternative name(s):

Beta-1,4-GalTase 4
Beta4Gal-T4
b4Gal-T4
UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 4
UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 4
Nal synthase
Beta-N-acetylglucosaminyl-glycolipid beta-1,4-galactosyltransferase

B4GALT4 SNPs

    To see your genotype, you should be logged in and have a file with your genotype uploaded.

  1. RS6438504 (B4GALT4) ??

Top Gene-Substance Interactions

B4GALT4 Interacts with These Diseases

Disease Score

Substances That Increase B4GALT4

Substances Interaction Organism Category

Substances That Decrease B4GALT4

Substances Interaction Organism Category

Conditions with Increased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Conditions with Decreased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Technical

The following transcription factors affect gene expression:

  • Arnt
  • Nkx2-5
  • GATA-1
  • GATA-2
  • GATA-3

Tissue specificity:

High expression in heart, placenta, kidney and pancreas; lower in brain, colon, lung, muscle, ovary, testis and uterus.

Gene Pathways:

  • Metabolic pathways
  • Metabolism
  • Disease
  • Metabolism of proteins
  • Glycosaminoglycan biosynthesis - keratan sulfate
  • Glycosphingolipid biosynthesis - lacto and neolacto series

Molecular Function:

  • Beta-N-Acetylglucosaminylglycopeptide Beta-1,4-Galactosyltransferase Activity
  • Galactosyltransferase Activity
  • Metal Ion Binding
  • N-Acetyllactosamine Synthase Activity

Biological Processes:

  • Carbohydrate Metabolic Process
  • Keratan Sulfate Biosynthetic Process
  • Membrane Lipid Metabolic Process
  • Protein Glycosylation

Drug Bank:

  • N-Acetyl-D-Glucosamine
*synonyms

Synonyms/Aliases/Alternative Names of the Gene:

hypothetical protein| UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide| Anapl_13128| AS27_09807| AS28_01480| B4Gal-T4| B4galt-IV| beta-1,4-galactosyltransferase IV| beta-1,4-GalTase 4| Beta4Gal-T4| beta4GalT-IV| beta-N-acetylglucosaminyl-glycolipid beta-1,4-galactosyltransferase 4| CB1_001373011| CH1073-177A15.1| EGK_11319| EH28_04212| fk70b01| H920_07838| M959_12443| MDA_GLEAN10002704| N300_13572| N301_03193| N302_08020| N303_06920| N305_06272| N306_11222| N307_09185| N308_09813| N309_10194| N310_00990| N311_04787| N312_04394| N320_10009| N321_13165| N322_00732| N324_03379| N325_09502| N326_00904| N327_01418| N328_12517| N329_07180| N330_02061| N332_01760| N333_05558| N334_08237| N335_05630| N336_04089| N339_02361| N340_08335| N341_00668| PAL_GLEAN10006506| PANDA_003284| TREES_T100013719| UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 4| UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 4| UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase 4| UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4| UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 4| UY3_09193| Y1Q_007360| Y956_11554| Z169_15756| b4galt4

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