The Function of B3GNT2
Beta-1,3-N-acetylglucosaminyltransferase involved in the synthesis of poly-N-acetyllactosamine. Catalyzes the initiation and elongation of poly-N-acetyllactosamine chains. Shows a marked preference for Gal(beta1-4)Glc(NAc)-based acceptors (PubMed:9892646). Probably constitutes the main polylactosamine synthase.
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Protein names
Recommended name:
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2Alternative name(s):
Beta-1,3-N-acetylglucosaminyltransferase 1BGnT-1
Beta-1,3-Gn-T1
Beta3Gn-T1
Beta-1,3-galactosyltransferase 7
Beta-1,3-GalTase 7
Beta3Gal-T7
Beta3GalT7
b3Gal-T7
Beta-3-Gx-T7
UDP-Gal:beta-GlcNAc beta-1,3-galactosyltransferase 7
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
BGnT-2
Beta-1,3-Gn-T2
Beta-1,3-N-acetylglucosaminyltransferase 2
Beta3Gn-T2
UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase 7
- RS11900673 (B3GNT2) ??
- RS13385025 (B3GNT2) ??
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Top Gene-Substance Interactions
Substances That Increase B3GNT2
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Substances That Decrease B3GNT2
| Substances | Interaction | Organism | Category |
Conditions with Increased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Conditions with Decreased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Technical
The following transcription factors affect gene expression:
Tissue specificity:
Ubiquitous.
Gene Pathways:
Caution:
Was indicated as B3Gal-T6 in submitted DNA entries.
Molecular Function:
- N-Acetyllactosaminide Beta-1,3-N-Acetylglucosaminyltransferase Activity
- Udp-Galactose:Beta-N-Acetylglucosamine Beta-1,3-Galactosyltransferase Activity
Biological Processes:
- Axon Guidance
- Keratan Sulfate Biosynthetic Process
- O-Glycan Processing
- Poly-N-Acetyllactosamine Biosynthetic Process
- Sensory Perception Of Smell