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  3. B3GNT2

B3GNT2 (UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2)

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The Function of B3GNT2

Beta-1,3-N-acetylglucosaminyltransferase involved in the synthesis of poly-N-acetyllactosamine. Catalyzes the initiation and elongation of poly-N-acetyllactosamine chains. Shows a marked preference for Gal(beta1-4)Glc(NAc)-based acceptors (PubMed:9892646). Probably constitutes the main polylactosamine synthase.

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Protein names

Recommended name:

N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2

Alternative name(s):

Beta-1,3-N-acetylglucosaminyltransferase 1
BGnT-1
Beta-1,3-Gn-T1
Beta3Gn-T1
Beta-1,3-galactosyltransferase 7
Beta-1,3-GalTase 7
Beta3Gal-T7
Beta3GalT7
b3Gal-T7
Beta-3-Gx-T7
UDP-Gal:beta-GlcNAc beta-1,3-galactosyltransferase 7
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2
BGnT-2
Beta-1,3-Gn-T2
Beta-1,3-N-acetylglucosaminyltransferase 2
Beta3Gn-T2
UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase 7

B3GNT2 SNPs

    To see your genotype, you should be logged in and have a file with your genotype uploaded.

  1. RS11900673 (B3GNT2) ??
  2. RS13385025 (B3GNT2) ??

Top Gene-Substance Interactions

Substances That Increase B3GNT2

Substances Interaction Organism Category

Substances That Decrease B3GNT2

Substances Interaction Organism Category

Conditions with Increased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Conditions with Decreased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Technical

The following transcription factors affect gene expression:

  • HNF-1A
  • Max
  • HNF-1
  • STAT5A
  • STAT5B
  • c-Myc
  • Msx-1

Tissue specificity:

Ubiquitous.

Gene Pathways:

  • Metabolic pathways
  • Metabolism
  • Disease
  • Metabolism of proteins
  • Glycosaminoglycan biosynthesis - keratan sulfate
  • Glycosphingolipid biosynthesis - lacto and neolacto series

Caution:

Was indicated as B3Gal-T6 in submitted DNA entries.

Molecular Function:

  • N-Acetyllactosaminide Beta-1,3-N-Acetylglucosaminyltransferase Activity
  • Udp-Galactose:Beta-N-Acetylglucosamine Beta-1,3-Galactosyltransferase Activity

Biological Processes:

  • Axon Guidance
  • Keratan Sulfate Biosynthetic Process
  • O-Glycan Processing
  • Poly-N-Acetyllactosamine Biosynthetic Process
  • Sensory Perception Of Smell
*synonyms

Synonyms/Aliases/Alternative Names of the Gene:

hypothetical protein| B3GNT7| UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7| UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1| 3-Gn-T1| 3-Gn-T2| Anapl_05466| AS27_12722| AS28_02286| B3Galt6| B3GNT| B3gnt1| B3GN-T2| B3GNT-2| beta-1| beta-1,3-Gn-T1| beta-1,3-Gn-T2| beta-1,3-N-acetylglucosaminyltransferase 1| beta-1,3-N-acetylglucosaminyltransferase 2| beta-1,3-N-acetylglucosaminyltransferase bGnT-1| beta-1,3-N-acetylglucosaminyltransferase bGnT-2| Beta3gnt| beta3Gn-T1| beta3Gn-T2| BGnT1| BGnT-1| BGnT-2| BGNT2| CB1_001505014| EGK_05370| H920_17524| N300_05349| N301_02032| N302_08610| N303_01267| N305_07520| N306_01454| N307_07890| N308_08520| N309_07445| N311_09321| N312_00037| N320_10944| N322_02280| N325_02838| N326_04959| N327_07863| N328_01292| N329_11448| N331_05756| N332_07851| N333_02803| N334_03895| N335_14145| N336_09897| N339_12960| N340_03370| N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2| PAL_GLEAN10021217| TREES_T100000695| UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 6| UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2-like protein| UY3_09952| Y1Q_008480| Y956_07302| Z169_08742| b3gnt2

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