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  3. ASIC2

ASIC2 (Acid sensing ion channel subunit 2)

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The Function of ASIC2

Cation channel with high affinity for sodium, which is gated by extracellular protons and inhibited by the diuretic amiloride. Also permeable for Li(+) and K(+). Generates a biphasic current with a fast inactivating and a slow sustained phase. Heteromeric channel assembly seems to modulate.

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Protein names

Recommended name:

Acid-sensing ion channel 2

Short name:

BNC1

Alternative name(s):

ASIC2
Amiloride-sensitive brain sodium channel
Amiloride-sensitive cation channel 1, neuronal
Amiloride-sensitive cation channel neuronal 1
Brain sodium channel 1
BNaC1
Mammalian degenerin homolog

ASIC2 SNPs

    To see your genotype, you should be logged in and have a file with your genotype uploaded.

  1. RS11650066 (ASIC2) ??
  2. RS116908816 (ASIC2) ??
  3. RS117364231 (ASIC2) ??
  4. RS1354492 (ASIC2) ??
  5. RS17808461 (ASIC2) ??
  6. RS320637 (ASIC2) ??
  7. RS72819126 (ASIC2) ??
  8. RS9901756 (ASIC2) ??

Top Gene-Substance Interactions

ASIC2 Interacts with These Diseases

Disease Score

Substances That Increase ASIC2

Substances Interaction Organism Category

Substances That Decrease ASIC2

Substances Interaction Organism Category

Conditions with Increased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Conditions with Decreased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

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