The Function of ASIC2
Cation channel with high affinity for sodium, which is gated by extracellular protons and inhibited by the diuretic amiloride. Also permeable for Li(+) and K(+). Generates a biphasic current with a fast inactivating and a slow sustained phase. Heteromeric channel assembly seems to modulate.
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Protein names
Recommended name:
Acid-sensing ion channel 2Short name:
BNC1Alternative name(s):
ASIC2Amiloride-sensitive brain sodium channel
Amiloride-sensitive cation channel 1, neuronal
Amiloride-sensitive cation channel neuronal 1
Brain sodium channel 1
BNaC1
Mammalian degenerin homolog
- RS11650066 (ASIC2) ??
- RS116908816 (ASIC2) ??
- RS117364231 (ASIC2) ??
- RS1354492 (ASIC2) ??
- RS17808461 (ASIC2) ??
- RS320637 (ASIC2) ??
- RS72819126 (ASIC2) ??
- RS9901756 (ASIC2) ??
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Top Gene-Substance Interactions
ASIC2 Interacts with These Diseases
| Disease | Score |
Substances That Increase ASIC2
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Substances That Decrease ASIC2
| Substances | Interaction | Organism | Category |
Conditions with Increased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Conditions with Decreased Gene Activity
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