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  3. ASB2

ASB2 (Ankyrin repeat and SOCS box containing 2)

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The Function of ASB2

Isoform 2: Involved in myogenic differentiation and targets filamin FLNB for proteasomal degradation but not filamin FLNA.

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ASB2 SNPs

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  1. RS11844114 (ASB2) ??
  2. RS79797842 (ASB2) ??

Top Gene-Substance Interactions

Substances That Increase ASB2

Substances Interaction Organism Category

Substances That Decrease ASB2

Substances Interaction Organism Category

Conditions with Increased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Conditions with Decreased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Technical

The following transcription factors affect gene expression:

  • NF-kappaB
  • NF-kappaB1
  • SREBP-1a
  • YY1
  • SREBP-1c
  • SREBP-1b
  • NF-kappaB2

Induction:

By all-trans retinoic acid (ATRA).

Molecular Function:

  • Ubiquitin Protein Ligase Activity

Biological Processes:

  • Intracellular Signal Transduction
  • Mitophagy In Response To Mitochondrial Depolarization
  • Myoblast Differentiation
  • Positive Regulation Of Defense Response To Virus By Host
  • Protein Polyubiquitination
  • Protein Ubiquitination Involved In Ubiquitin-Dependent Protein Catabolic Process
  • Signal Transduction
  • Skeletal Muscle Cell Differentiation
  • Xenophagy
*synonyms

Synonyms/Aliases/Alternative Names of the Gene:

hypothetical protein| Anapl_03298| ankyrin repeat and SOCS box-containing 2| ankyrin repeat and SOCS box-containing protein 2| ankyrin repeat and SOCS box-containing protein 2a| Ankyrin repeat and SOCS box protein 2| ankyrin repeat-containing SOCS box protein 2| AS27_04568| AS28_10535| ASB-2| CB1_000726097| D623_10025281| H920_17280| I79_014487| M91_13724| M959_10891| MDA_GLEAN10006310| N301_02221| N302_00093| N303_15540| N305_01298| N307_08463| N308_06917| N309_06341| N310_07227| N311_07889| N312_09262| N320_04529| N322_13404| N324_03248| N325_08555| N327_09198| N329_08621| N331_06000| N332_03129| N333_07486| N335_14077| N336_04316| N339_01389| N340_08599| N341_12532| PAL_GLEAN10020796| PANDA_013451| TREES_T100005843| UY3_10493| Y1Q_009119| Y956_05064| Z169_08771| asb2

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