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  3. ARID2

ARID2 (AT-rich interaction domain 2)

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The Function of ARID2

Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Required for the stability of the SWI/SNF chromatin remodeling complex SWI/SNF-B (PBAF). May be involved in targeting the complex to different genes. May be involved in regulating transcriptional activation of cardiac genes.

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Protein names

Recommended name:

AT-rich interactive domain-containing protein 2

Short name:

BAF200

Alternative name(s):

ARID domain-containing protein 2
BRG1-associated factor 200
Zinc finger protein with activation potential
Zipzap/p200

ARID2 SNPs

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  1. RS247929 (ARID2) ??

Top Gene-Substance Interactions

Substances That Increase ARID2

Substances Interaction Organism Category

Substances That Decrease ARID2

Substances Interaction Organism Category

Conditions with Increased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Conditions with Decreased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Technical

The following transcription factors affect gene expression:

  • Nkx2-5

Tissue specificity:

Highly expressed in heart and testis.

Gene Pathways:

  • Chromatin organization

Developmental stage:

Up-regulated in adult heart (at protein level).

Molecular Function:

  • Dna Binding
  • Metal Ion Binding

Biological Processes:

  • Covalent Chromatin Modification
  • Negative Regulation Of Cell Migration
  • Negative Regulation Of Cell Proliferation
  • Nucleosome Disassembly
  • Regulation Of Transcription, Dna-Templated
  • Transcription, Dna-Templated
*synonyms

Synonyms/Aliases/Alternative Names of the Gene:

hypothetical protein| Anapl_08000| ARID domain-containing protein 2| AS27_10253| AS28_01020| AT rich interactive domain 2 (Arid-rfx like)| AT rich interactive domain 2 (ARID, RFX-like)| AT-rich interactive domain-containing protein 2| BAF200| BRG1-associated factor 200| CB1_001331013| D623_10029493| EGK_03551| fi45a01| GW7_00211| H920_11361| I79_019659| M91_03538| M959_00847| MDA_GLEAN10022525| N300_12304| N301_12062| N303_01039| N305_02784| N308_12790| N309_08688| N312_07849| N320_12476| N322_07632| N325_07013| N326_08883| N328_11295| N329_12452| N330_02028| N332_05483| N335_08977| N336_06993| p200| PAL_GLEAN10010041| PANDA_016976| TREES_T100021319| UY3_10948| Y1Q_017690| Y956_02922| Z169_08515| zinc finger protein with activation potential| zipzap| zipzap/p200| arid2

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