The Function of ARHGAP35
Represses transcription of the glucocorticoid receptor by binding to the cis-acting regulatory sequence 5'-GAGAAAAGAAACTGGAGAAACTC-3' (PubMed:1894621). May participate in the regulation of retinal development and degeneration. May transduce signals from p21-ras to the nucleus, acting via the ras GTPase-activating protein (GAP) (By similarity). Modulates Rho GTPase-dependent F-actin polymerization and is involved in the positive regulation of ciliogenesis and cilia elongation.
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Protein names
Recommended name:
Rho GTPase-activating protein 35Short name:
GRF-1Alternative name(s):
Glucocorticoid receptor DNA-binding factor 1Glucocorticoid receptor repression factor 1
Rho GAP p190A
p190-A
- RS10164289 (ARHGAP35) ??
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Top Gene-Substance Interactions
Substances That Increase ARHGAP35
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Substances That Decrease ARHGAP35
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Conditions with Increased Gene Activity
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Conditions with Decreased Gene Activity
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