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  3. APBB1IP

APBB1IP (Amyloid beta precursor protein binding family B member 1 interacting protein)

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The Function of APBB1IP

Appears to function in the signal transduction from Ras activation to actin cytoskeletal remodeling. Suppresses insulin-induced promoter activities through AP1 and SRE. Mediates Rap1-induced adhesion.

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Protein names

Recommended name:

Amyloid beta A4 precursor protein-binding family B member 1-interacting protein

Short name:

RIAM

Alternative name(s):

APBB1-interacting protein 1
Proline-rich EVH1 ligand 1
PREL-1
Proline-rich protein 73
Rap1-GTP-interacting adapter molecule
Retinoic acid-responsive proline-rich protein 1
RARP-1

APBB1IP SNPs

    To see your genotype, you should be logged in and have a file with your genotype uploaded.

  1. RS2992257 (APBB1IP) ??
  2. RS786870 (APBB1IP) ??

Top Gene-Substance Interactions

Substances That Increase APBB1IP

Substances Interaction Organism Category

Substances That Decrease APBB1IP

Substances Interaction Organism Category

Conditions with Increased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Conditions with Decreased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Technical

The following transcription factors affect gene expression:

  • AP-1
  • c-Jun

Tissue specificity:

Widely expressed with high expression in thymus, spleen, lymph node, bone marrow and peripheral leukocytes.

Gene Pathways:

  • Signal Transduction
  • Hemostasis

Induction:

By all-trans-retinoic acid (ATRA).

Biological Processes:

  • Positive Regulation Of Cell Adhesion
  • Signal Transduction
  • T Cell Activation Via T Cell Receptor Contact With Antigen Bound To Mhc Molecule On Antigen Presenting Cell
*synonyms

Synonyms/Aliases/Alternative Names of the Gene:

hypothetical protein| A306_14911| amyloid beta (A4) precursor protein-binding, family B, member 1| amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein| Amyloid beta A4 precursor protein-binding family B member 1-interacting protein| APBB1-interacting protein 1| AS27_09240| AS28_10516| GW7_03485| H920_19671| I79_014057| INAG1| M91_07112| M959_03661| MDA_GLEAN10002610| N300_06450| N301_00436| N302_03961| N303_01961| N305_13860| N307_09091| N308_01675| N309_11164| N310_01474| N311_03054| N312_09602| N321_06042| N324_08463| N325_04845| N326_01384| N328_10995| N329_06566| N330_14106| N331_12424| N333_05825| N334_02040| N335_14550| N339_00490| N340_02985| N341_02142| PAL_GLEAN10015882| PANDA_017359| PREL1| PREL-1| proline rich EVH1 ligand 1| proline-rich EVH1 ligand 1| proline-rich protein 48| proline-rich protein 73| Prp48| rap1-GTP-interacting adapter molecule| Rap1-GTP-interacting adaptor molecule| Rap1-interacting adaptor molecule| RARP1| RARP-1| retinoic acid-responsive proline-rich protein 1| RIAM| TREES_T100004939| UY3_05831| Y1Q_005989| Y956_00843| Z169_02057| apbb1ip

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