• Navigation
  • Register My DNA Kit
  • Features
  • Pricing
  • FAQ
  • About
  • Labs
  • Login
  • Get started
  1. Home
  2. Genes
  3. AP3S2

AP3S2 (Adaptor related protein complex 3 sigma 2 subunit)

Loading...

The Function of AP3S2

Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.

0 users want this gene increased, 0 users want it decreased

Protein names

Recommended name:

AP-3 complex subunit sigma-2

Alternative name(s):

AP-3 complex subunit sigma-3B
Adaptor-related protein complex 3 subunit sigma-2
Sigma-3B-adaptin
Sigma3B-adaptin
Sigma-adaptin 3b

AP3S2 SNPs

    To see your genotype, you should be logged in and have a file with your genotype uploaded.

  1. RS2028299 (AP3S2) ??

Top Gene-Substance Interactions

Substances That Increase AP3S2

Substances Interaction Organism Category

Substances That Decrease AP3S2

Substances Interaction Organism Category

Conditions with Increased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Conditions with Decreased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Technical

The following transcription factors affect gene expression:

  • PPAR-gamma1
  • PPAR-gamma2
  • Pax-6
  • NRF-2
  • FAC1
  • FOXF2
  • NF-1
  • Roaz

Tissue specificity:

Present in all adult tissues examined.

Gene Pathways:

  • Lysosome

Molecular Function:

  • Protein Transporter Activity

Biological Processes:

  • Anterograde Axonal Transport
  • Anterograde Synaptic Vesicle Transport
  • Intracellular Protein Transport
*synonyms

Synonyms/Aliases/Alternative Names of the Gene:

hypothetical protein| adapter-related protein complex 3 sigma-2 subunit| adapter-related protein complex 3 subunit sigma-2| adaptor complex sigma3B| adaptor-related protein complex 3, sigma 2 subunit| adaptor-related protein complex 3 sigma 2 subunit-like| adaptor-related protein complex 3 subunit sigma-2| adaptor-related protein complex AP-3, sigma 2 subunit| AP-3 complex sigma-3B subunit| AP-3 complex subunit sigma-2| AP-3 complex subunit sigma-2-like protein| AP-3 complex subunit sigma-3B| AP3S3| AS27_14942| C7H15orf38| clathrin-associated/assembly/adaptor protein, small 4, 22-kD| D623_10004294| EGK_17825| H920_03978| MDA_GLEAN10002557| N302_04942| N303_08285| N305_13076| N307_09623| N310_05908| N327_07399| PAL_GLEAN10009491| putative adaptor-related protein complex 3 sigma 2 subunit| [s]3B| sigma3b| sigma 3B| sigma-3B-adaptin| sigma3B-adaptin| sigma-adaptin 3b| UPF0552 protein C15orf38 homolog| UPF0552 protein C15orf38-like| Y956_09624| ap3s2

Policies

  • Terms of Service
  • Platform Consent
  • Privacy Policy
  • Disclaimer

About

  • Customer Support
  • Our Team
  • Affiliate Program

Navigation

  • Homepage
  • DNA Wellness Reports
  • Personalized Genetics Blog
  • Register your DNA Test Kit
  • Login
  • Careers
GET STARTED
  • SelfDecode is a personalized health report service, which enables users to obtain detailed information and reports based on their genome. SelfDecode does not treat, diagnose or cure any conditions, but is for informational and educational purposes alone.
SelfDecode © 2021 All Rights Reserved