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  3. ALPK1

ALPK1 (Alpha kinase 1)

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The Function of ALPK1

Kinase that recognizes phosphorylation sites in which the surrounding peptides have an alpha-helical conformation.

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Protein names

Recommended name:

Alpha-protein kinase 1

Alternative name(s):

Chromosome 4 kinase
Lymphocyte alpha-protein kinase

ALPK1 SNPs

    To see your genotype, you should be logged in and have a file with your genotype uploaded.

  1. RS11726117 (ALPK1) ??
  2. RS4833407 (ALPK1) ??
  3. RS6838440 (ALPK1) ??

Top Gene-Substance Interactions

ALPK1 Interacts with These Diseases

Disease Score

Substances That Increase ALPK1

Substances Interaction Organism Category

Substances That Decrease ALPK1

Substances Interaction Organism Category

Conditions with Increased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Conditions with Decreased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Technical

The following transcription factors affect gene expression:

  • NF-kappaB
  • HNF-1A
  • FOXO4
  • NF-kappaB1
  • HNF-1
  • RelA

Tissue specificity:

Highly expressed in liver.

Molecular Function:

  • Atp Binding
  • Protein Serine/Threonine Kinase Activity

Biological Processes:

  • Mitophagy In Response To Mitochondrial Depolarization
  • Positive Regulation Of Defense Response To Virus By Host
  • Xenophagy
*synonyms

Synonyms/Aliases/Alternative Names of the Gene:

hypothetical protein| alpha-kinase 1| Alpha-protein kinase 1| Alpha-protein kinase 1-like protein| Anapl_12246| AS27_09065| AS28_02642| CB1_000165011| chromosome 4 kinase| H920_12727| I79_021606| LAK| lymphocyte alpha-kinase| lymphocyte alpha-protein kinase| M91_07238| M959_08667| N300_02086| N301_15150| N302_13230| N303_14702| N305_11757| N306_09931| N307_15111| N308_12135| N309_08532| N310_04697| N312_09435| N320_08355| N321_01201| N324_04525| N327_13057| N328_04730| N329_09382| N330_01355| N331_08971| N332_11714| N333_04747| N334_08672| N335_05758| N336_02786| N339_02847| N340_04126| N341_03825| PANDA_005881| RGD1304613| UY3_01931| Y1Q_008193| Y956_11992| Z169_13792| zmp:0000001108| alpk1

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