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  3. ALDOA

ALDOA (Aldolase, fructose-bisphosphate A)

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The Function of ALDOA

Plays a key role in glycolysis and gluconeogenesis. In addition, may also function as scaffolding protein.

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Protein names

Recommended name:

Fructose-bisphosphate aldolase A

Alternative name(s):

Lung cancer antigen NY-LU-1
Muscle-type aldolase

Top Gene-Substance Interactions

ALDOA Interacts with These Diseases

Disease Score

Substances That Increase ALDOA

Substances Interaction Organism Category

Substances That Decrease ALDOA

Substances Interaction Organism Category

Conditions with Increased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Conditions with Decreased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Technical

The following transcription factors affect gene expression:

  • Sp1
  • NF-1

Gene Pathways:

  • Metabolic pathways
  • Metabolism
  • Disease
  • Fructose and mannose metabolism
  • Hemostasis
  • Glycolysis / Gluconeogenesis
  • Pentose phosphate pathway

Molecular Function:

  • Actin Binding
  • Cadherin Binding Involved In Cell-Cell Adhesion
  • Cytoskeletal Protein Binding
  • Fructose Binding
  • Fructose-Bisphosphate Aldolase Activity
  • Identical Protein Binding
  • Poly(A) Rna Binding
  • Tubulin Binding

Biological Processes:

  • Actin Filament Organization
  • Atp Biosynthetic Process
  • Canonical Glycolysis
  • Fructose 1,6-Bisphosphate Metabolic Process
  • Fructose Metabolic Process
  • Gluconeogenesis
  • Glycolytic Process
  • Muscle Cell Cellular Homeostasis
  • Platelet Degranulation
  • Protein Homotetramerization
  • Regulation Of Cell Shape
  • Striated Muscle Contraction
*synonyms

Synonyms/Aliases/Alternative Names of the Gene:

hypothetical protein| ALDA| Aldo1| Aldo-1| aldolase| aldolase 1, A isoform| aldolase A, fructose-bisphosphate| aldolase C| D623_10014446| epididymis secretory sperm binding protein Li 87p| fructose-1,6-bisphosphate aldolase A| fructose-1,6-bisphosphate triosephosphate-lyase| fructose-bisphosphate aldolase A| GSD12| HEL-S-87p| keratin-associated protein 10-2| lung cancer antigen NY-LU-1| MDA_GLEAN10001857| muscle-type aldolase| PAL_GLEAN10011860| PANDA_017154| RNALDOG5| TREES_T100000521| Y1Q_030067| aldoa

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