The Function of ALB
Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc.
0 users want this gene increased,
0 users want it decreased
Protein names
Recommended name:
Serum albuminTop Gene-Substance Interactions
ALB Interacts with These Diseases
| Disease | Score |
Substances That Increase ALB
| Substances | Interaction | Organism | Category |
Substances That Decrease ALB
| Substances | Interaction | Organism | Category |
Conditions with Increased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
|---|
Conditions with Decreased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
|---|
Technical
The following transcription factors affect gene expression:
Tissue specificity:
Plasma.
Gene Pathways:
Caution:
A peptide arising from positions 166 to 174 was originally (PubMed:3087352 and PubMed:2437111) termed neurotensin-related peptide (NRP) or kinetensin and was thought to regulate fat digestion, lipid absorption, and blood flow.
Molecular Function:
- Antioxidant Activity
- Chaperone Binding
- Copper Ion Binding
- Dna Binding
- Drug Binding
- Fatty Acid Binding
- Identical Protein Binding
- Pyridoxal Phosphate Binding
- Toxic Substance Binding
- Zinc Ion Binding
Biological Processes:
- Bile Acid And Bile Salt Transport
- Cellular Response To Starvation
- Hemolysis By Symbiont Of Host Erythrocytes
- Lipoprotein Metabolic Process
- Maintenance Of Mitochondrion Location
- Negative Regulation Of Apoptotic Process
- Negative Regulation Of Programmed Cell Death
- Platelet Degranulation
- Receptor-Mediated Endocytosis
- Retina Homeostasis
- Sodium-Independent Organic Anion Transport
- Transport
- Positive Regulation Of Circadian Sleep/Wake Cycle, Non-Rem Sleep
- Response To Mercury Ion
- Response To Nutrient
- Response To Organic Substance
- Response To Platinum Ion
Drug Bank:
- Acetylsalicylic Acid
- Captopril
- Cefalotin
- Enzalutamide
- Erlotinib
- Gadobenate Dimeglumine
- Hyaluronidase
- Hyaluronidase (Human Recombinant)
- Imatinib
- Liothyronine
- Liotrix
- Norethisterone
- Pethidine
- Pipotiazine
- Prasugrel
- Rifampicin
- Acenocoumarol
- Acepromazine
- Acitretin
- Alfentanil
- Amitriptyline
- Ampicillin
- Bismuth Subsalicylate
- Canagliflozin
- Cefazolin
- Cefmetazole
- Cefonicid
- Cefotaxime
- Cefotetan
- Cefpiramide
- Ceftriaxone
- Celecoxib
- Chlorpromazine
- Clomipramine
- Clonazepam
- Cloxacillin
- Desflurane
- Diclofenac
- Diflunisal
- Digitoxin
- Dronedarone
- Erythromycin
- Estradiol
- Estrone
- Estropipate
- Ethacrynic Acid
- Etodolac
- Fluorouracil
- Fluoxetine
- Flurbiprofen
- Fosphenytoin
- Fospropofol
- Furosemide
- Gatifloxacin
- Gefitinib
- Gliclazide
- Glyburide
- Halothane
- Ibuprofen
- Insulin Detemir
- Iodipamide
- Irinotecan
- Isoflurane
- Ivacaftor
- Ketazolam
- Levothyroxine
- Losartan
- Macitentan
- Magnesium Salicylate
- Methacycline
- Methotrexate
- Mirabegron
- Mycophenolate Mofetil
- Naloxone
- Naproxen
- Nateglinide
- Nortriptyline
- Oleic Acid
- Oxcarbazepine
- Oxymetholone
- Phenprocoumon
- Phenytoin
- Piroxicam
- Prednisone
- Probenecid
- Propofol
- Repaglinide
- Rosuvastatin
- Sodium Lauryl Sulfate
- Vandetanib
- Vemurafenib
- Vismodegib
- Xanthophyll
- Rosiglitazone
- Rufinamide
- Salicylic Acid
- Saquinavir
- Simeprevir
- Sucralfate
- Sulfamerazine
- Sulfamethazine
- Sulfamethizole
- Sulfamethoxazole
- Tacrolimus
- Telaprevir
- Testosterone
- Tetracycline
- Thioproperazine
- Thiothixene
- Tofacitinib
- Ulipristal
- Valsartan
- Vancomycin
- Zidovudine
- Abiraterone
- Auranofin
- Cefoperazone
- Cephalexin
- Diazepam
- Enflurane
- Fenoprofen
- Gadofosveset Trisodium
- Indomethacin
- Ketoprofen
- Methyltestosterone
- Olanzapine
- Pitavastatin
- Riociguat
- Sevoflurane
- Sulindac
- Tocainide
- Warfarin