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  3. ALB

ALB (Albumin)

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The Function of ALB

Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc.

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Protein names

Recommended name:

Serum albumin

Top Gene-Substance Interactions

ALB Interacts with These Diseases

Disease Score

Substances That Increase ALB

Substances Interaction Organism Category

Substances That Decrease ALB

Substances Interaction Organism Category

Conditions with Increased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Conditions with Decreased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Technical

The following transcription factors affect gene expression:

  • PPAR-gamma1
  • PPAR-gamma2
  • STAT3
  • C/EBPalpha
  • HNF-4alpha1
  • HNF-4alpha2
  • p300

Tissue specificity:

Plasma.

Gene Pathways:

  • Metabolism
  • Hemostasis
  • Transmembrane transport of small molecules

Caution:

A peptide arising from positions 166 to 174 was originally (PubMed:3087352 and PubMed:2437111) termed neurotensin-related peptide (NRP) or kinetensin and was thought to regulate fat digestion, lipid absorption, and blood flow.

Molecular Function:

  • Antioxidant Activity
  • Chaperone Binding
  • Copper Ion Binding
  • Dna Binding
  • Drug Binding
  • Fatty Acid Binding
  • Identical Protein Binding
  • Pyridoxal Phosphate Binding
  • Toxic Substance Binding
  • Zinc Ion Binding

Biological Processes:

  • Bile Acid And Bile Salt Transport
  • Cellular Response To Starvation
  • Hemolysis By Symbiont Of Host Erythrocytes
  • Lipoprotein Metabolic Process
  • Maintenance Of Mitochondrion Location
  • Negative Regulation Of Apoptotic Process
  • Negative Regulation Of Programmed Cell Death
  • Platelet Degranulation
  • Receptor-Mediated Endocytosis
  • Retina Homeostasis
  • Sodium-Independent Organic Anion Transport
  • Transport
  • Positive Regulation Of Circadian Sleep/Wake Cycle, Non-Rem Sleep
  • Response To Mercury Ion
  • Response To Nutrient
  • Response To Organic Substance
  • Response To Platinum Ion

Drug Bank:

  • Acetylsalicylic Acid
  • Captopril
  • Cefalotin
  • Enzalutamide
  • Erlotinib
  • Gadobenate Dimeglumine
  • Hyaluronidase
  • Hyaluronidase (Human Recombinant)
  • Imatinib
  • Liothyronine
  • Liotrix
  • Norethisterone
  • Pethidine
  • Pipotiazine
  • Prasugrel
  • Rifampicin
  • Acenocoumarol
  • Acepromazine
  • Acitretin
  • Alfentanil
  • Amitriptyline
  • Ampicillin
  • Bismuth Subsalicylate
  • Canagliflozin
  • Cefazolin
  • Cefmetazole
  • Cefonicid
  • Cefotaxime
  • Cefotetan
  • Cefpiramide
  • Ceftriaxone
  • Celecoxib
  • Chlorpromazine
  • Clomipramine
  • Clonazepam
  • Cloxacillin
  • Desflurane
  • Diclofenac
  • Diflunisal
  • Digitoxin
  • Dronedarone
  • Erythromycin
  • Estradiol
  • Estrone
  • Estropipate
  • Ethacrynic Acid
  • Etodolac
  • Fluorouracil
  • Fluoxetine
  • Flurbiprofen
  • Fosphenytoin
  • Fospropofol
  • Furosemide
  • Gatifloxacin
  • Gefitinib
  • Gliclazide
  • Glyburide
  • Halothane
  • Ibuprofen
  • Insulin Detemir
  • Iodipamide
  • Irinotecan
  • Isoflurane
  • Ivacaftor
  • Ketazolam
  • Levothyroxine
  • Losartan
  • Macitentan
  • Magnesium Salicylate
  • Methacycline
  • Methotrexate
  • Mirabegron
  • Mycophenolate Mofetil
  • Naloxone
  • Naproxen
  • Nateglinide
  • Nortriptyline
  • Oleic Acid
  • Oxcarbazepine
  • Oxymetholone
  • Phenprocoumon
  • Phenytoin
  • Piroxicam
  • Prednisone
  • Probenecid
  • Propofol
  • Repaglinide
  • Rosuvastatin
  • Sodium Lauryl Sulfate
  • Vandetanib
  • Vemurafenib
  • Vismodegib
  • Xanthophyll
  • Rosiglitazone
  • Rufinamide
  • Salicylic Acid
  • Saquinavir
  • Simeprevir
  • Sucralfate
  • Sulfamerazine
  • Sulfamethazine
  • Sulfamethizole
  • Sulfamethoxazole
  • Tacrolimus
  • Telaprevir
  • Testosterone
  • Tetracycline
  • Thioproperazine
  • Thiothixene
  • Tofacitinib
  • Ulipristal
  • Valsartan
  • Vancomycin
  • Zidovudine
  • Abiraterone
  • Auranofin
  • Cefoperazone
  • Cephalexin
  • Diazepam
  • Enflurane
  • Fenoprofen
  • Gadofosveset Trisodium
  • Indomethacin
  • Ketoprofen
  • Methyltestosterone
  • Olanzapine
  • Pitavastatin
  • Riociguat
  • Sevoflurane
  • Sulindac
  • Tocainide
  • Warfarin
*synonyms

Synonyms/Aliases/Alternative Names of the Gene:

hypothetical protein| A306_06617| Alb1| Alb-1| alberich| albumin 1| Albza| alpha-livetin| AS27_10815| AS28_07759| BCL002| BSA| CSA| GW7_11087| H920_18017| HSA| I79_025220| N300_02121| N301_09369| N302_14878| N303_05823| N305_12782| N306_01286| N307_08092| N309_11365| N311_04327| N320_07377| N321_03763| N322_12131| N328_06103| N332_03122| N335_06786| N336_00997| N340_14592| N341_01277| PAL_GLEAN10004316| PANDA_018508| preproalbumin| preproalbumin (serum albumin)| pre-pro serum albumin| PRO0883| PRO0903| PRO1341| Qlv-U377A-G8| Serum albumin| Y956_03391| alb

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