The Function of AK1
Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Also displays broad nucleoside diphosphate kinase activity. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
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Protein names
Recommended name:
Adenylate kinase isoenzyme 1Short name:
AK 1Alternative name(s):
ATP-AMP transphosphorylase 1ATP:AMP phosphotransferase
Adenylate monophosphate kinase
Myokinase
- RS7865146 (AK1) ??
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Top Gene-Substance Interactions
AK1 Interacts with These Diseases
| Disease | Score |
Substances That Increase AK1
| Substances | Interaction | Organism | Category |
Substances That Decrease AK1
| Substances | Interaction | Organism | Category |
Conditions with Increased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Conditions with Decreased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Technical
The following transcription factors affect gene expression:
Gene Pathways:
Molecular Function:
Biological Processes:
- Nucleoside Diphosphate Phosphorylation
- Adp Biosynthetic Process
- Cell Cycle Arrest
- Nucleoside Triphosphate Biosynthetic Process
- Nucleobase-Containing Small Molecule Interconversion
- Amp Metabolic Process
- Atp Metabolic Process