Summary of ADH1C
This gene encodes for the protein Alcohol Dehydrogenase 1C [R]. The protein plays an important role in detoxification and breaking down ethanol [R]. Lower protein levels will lead to lower ability to break down toxins and metabolize alcohol. Reduced ability to break down toxins may lead to neurodegerative diseases [R].
0 users want this gene increased,
0 users want it decreased
Protein names
Recommended name:
Alcohol dehydrogenase 1CAlternative name(s):
Alcohol dehydrogenase subunit gamma- RS1614972 (ADH1C) ??
- RS1662046 (ADH1C) ??
- RS1789891 (ADH1C) ??
- RS1789924 (ADH1C) ??
- RS283411 (ADH1C) ??
- RS283413 (ADH1C) ??
- RS56279505 (ADH1C) ??
- RS698 (ADH1C) ??
To see your genotype, you should be logged in and have a file with your genotype uploaded.
Top Gene-Substance Interactions
Substances That Increase ADH1C
| Substances | Interaction | Organism | Category |
Substances That Decrease ADH1C
| Substances | Interaction | Organism | Category |
Conditions with Increased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
|---|
Conditions with Decreased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
|---|
Technical
The following transcription factors affect gene expression:
Gene Pathways:
Cofactor:
Binds 2 Zn(2+) ions per subunit.
Molecular Function:
- Alcohol Dehydrogenase (Nad) Activity
- Alcohol Dehydrogenase Activity, Zinc-Dependent
- Retinol Dehydrogenase Activity
- Zinc Ion Binding