The Function of ACTR3
Functions as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the pointed end of the daughter actin filament. Plays a role in ciliogenesis.
0 users want this gene increased,
0 users want it decreased
Protein names
Recommended name:
Actin-related protein 3Alternative name(s):
Actin-like protein 3Top Gene-Substance Interactions
Substances That Increase ACTR3
| Substances | Interaction | Organism | Category |
Substances That Decrease ACTR3
| Substances | Interaction | Organism | Category |
Conditions with Increased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
|---|
Conditions with Decreased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
|---|
Technical
The following transcription factors affect gene expression:
Molecular Function:
Biological Processes:
- Arp2/3 Complex-Mediated Actin Nucleation
- Asymmetric Cell Division
- Cilium Assembly
- Ephrin Receptor Signaling Pathway
- Establishment Or Maintenance Of Cell Polarity
- Fc-Gamma Receptor Signaling Pathway Involved In Phagocytosis
- Meiotic Chromosome Movement Towards Spindle Pole
- Meiotic Cytokinesis
- Movement Of Cell Or Subcellular Component
- Spindle Localization