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  3. ACTR3

ACTR3 (ARP3 actin related protein 3 homolog)

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The Function of ACTR3

Functions as ATP-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Seems to contact the pointed end of the daughter actin filament. Plays a role in ciliogenesis.

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Protein names

Recommended name:

Actin-related protein 3

Alternative name(s):

Actin-like protein 3

Top Gene-Substance Interactions

Substances That Increase ACTR3

Substances Interaction Organism Category

Substances That Decrease ACTR3

Substances Interaction Organism Category

Conditions with Increased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Conditions with Decreased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Technical

The following transcription factors affect gene expression:

  • p53

Molecular Function:

  • Atp Binding
  • Structural Constituent Of Cytoskeleton

Biological Processes:

  • Arp2/3 Complex-Mediated Actin Nucleation
  • Asymmetric Cell Division
  • Cilium Assembly
  • Ephrin Receptor Signaling Pathway
  • Establishment Or Maintenance Of Cell Polarity
  • Fc-Gamma Receptor Signaling Pathway Involved In Phagocytosis
  • Meiotic Chromosome Movement Towards Spindle Pole
  • Meiotic Cytokinesis
  • Movement Of Cell Or Subcellular Component
  • Spindle Localization
*synonyms

Synonyms/Aliases/Alternative Names of the Gene:

hypothetical protein| actin-2| actin-like protein 3| actin-related protein 3| actin-related protein 3 homolog (yest)| ACTR3B| arp3| ARP3 actin-related protein 3| ARP3 actin-related protein 3 homolog| ARP3 actin-related protein 3 homolog B| ARP3 actin-related protein 3 homolog (yeast)| ARP3 actin-related protein 3-like protein| ARP3 (actin-related protein 3, yeast) homolog| AS27_08179| CB1_000826002| D623_10019686| GW7_07463| M91_18758| M959_08988| MDA_GLEAN10014250| N301_15899| N302_02303| N303_14871| N305_07502| N306_14180| N307_12048| N308_08202| N311_05077| N320_11107| N321_01096| N325_01632| N326_01686| N327_07302| N328_02589| N330_07829| N332_01343| N333_08349| N334_13457| N335_12647| N336_11662| N339_12340| N340_01065| N341_09826| PAL_GLEAN10025809| PANDA_015057| TREES_T100013176| UY3_08082| Y1Q_031746| Y956_06097| Z169_10127| actr3

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