The Function of ACTA2
Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells.
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Protein names
Recommended name:
Actin, aortic smooth muscleAlternative name(s):
Alpha-actin-2Cell growth-inhibiting gene 46 protein
- RS1800682 (ACTA2) ??
- RS1926203 (ACTA2) ??
- RS2234767 (ACTA2) ??
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Top Gene-Substance Interactions
ACTA2 Interacts with These Diseases
| Disease | Score |
Substances That Increase ACTA2
| Substances | Interaction | Organism | Category |
Substances That Decrease ACTA2
| Substances | Interaction | Organism | Category |
Conditions with Increased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
|---|
Conditions with Decreased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
|---|
Technical
The following transcription factors affect gene expression:
Gene Pathways:
Induction:
Up-regulated in response to enterovirus 71 (EV71) infection.
Molecular Function:
Biological Processes:
- Muscle Contraction
- Regulation Of Blood Pressure
- Response To Virus
- Positive Regulation Of Gene Expression
- Vascular Smooth Muscle Contraction
- Glomerular Mesangial Cell Development
- Mesenchyme Migration