The Function of ACOT11
Has acyl-CoA thioesterase activity towards medium (C12) and long-chain (C18) fatty acyl-CoA substrates.
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Protein names
Recommended name:
Acyl-coenzyme A thioesterase 11Short name:
BFITAlternative name(s):
Acyl-CoA thioesterase 11Acyl-CoA thioester hydrolase 11
Adipose-associated thioesterase
Brown fat-inducible thioesterase
- RS1368882 (ACOT11) ??
- RS2289015 (ACOT11) ??
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Top Gene-Substance Interactions
Substances That Increase ACOT11
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Substances That Decrease ACOT11
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Conditions with Increased Gene Activity
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Conditions with Decreased Gene Activity
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Technical
The following transcription factors affect gene expression:
Tissue specificity:
Isoform 1 is predominantly expressed in skeletal muscle, liver, testis, stomach, spleen, lung and brain. Isoform 2 is predominantly expressed in kidney, uterus, hibernoma and white adipose tissue.
Induction:
By cold exposure and repressed by heat exposure.
Molecular Function:
Biological Processes:
- Acyl-Coa Metabolic Process
- Fatty Acid Metabolic Process
- Intracellular Signal Transduction
- Long-Chain Fatty-Acyl-Coa Biosynthetic Process
- Response To Cold
- Response To Temperature Stimulus