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  3. ACADVL

ACADVL (Acyl-CoA dehydrogenase, very long chain)

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The Function of ACADVL

Active toward esters of long-chain and very long chain fatty acids such as palmitoyl-CoA, mysritoyl-CoA and stearoyl-CoA. Can accommodate substrate acyl chain lengths as long as 24 carbons, but shows little activity for substrates of less than 12 carbons.

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Protein names

Recommended name:

Very long-chain specific acyl-CoA dehydrogenase, mitochondrial

Short name:

VLCAD

ACADVL SNPs

    To see your genotype, you should be logged in and have a file with your genotype uploaded.

  1. RS2309689 (ACADVL) ??
  2. RS28934585 (ACADVL) ??

Top Gene-Substance Interactions

ACADVL Interacts with These Diseases

Disease Score

Substances That Increase ACADVL

Substances Interaction Organism Category

Substances That Decrease ACADVL

Substances Interaction Organism Category

Conditions with Increased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Conditions with Decreased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Technical

The following transcription factors affect gene expression:

  • PPAR-alpha

Gene Pathways:

  • Metabolic pathways
  • Metabolism
  • Fatty acid metabolism
  • Metabolism of proteins

Molecular Function:

  • Acyl-Coa Dehydrogenase Activity
  • Electron Carrier Activity
  • Fatty-Acyl-Coa Binding
  • Flavin Adenine Dinucleotide Binding
  • Long-Chain-Acyl-Coa Dehydrogenase Activity
  • Oxidoreductase Activity, Acting On The Ch-Ch Group Of Donors, With A Flavin As Acceptor
  • Very-Long-Chain-Acyl-Coa Dehydrogenase Activity

Biological Processes:

  • Energy Derivation By Oxidation Of Organic Compounds
  • Epithelial Cell Differentiation
  • Fatty Acid Beta-Oxidation
  • Fatty Acid Beta-Oxidation Using Acyl-Coa Dehydrogenase
  • Ire1-Mediated Unfolded Protein Response
  • Lipid Homeostasis
  • Negative Regulation Of Fatty Acid Biosynthetic Process
  • Negative Regulation Of Fatty Acid Oxidation
  • Regulation Of Cholesterol Metabolic Process
  • Temperature Homeostasis
  • Very Long-Chain Fatty Acid Catabolic Process
*synonyms

Synonyms/Aliases/Alternative Names of the Gene:

hypothetical protein| ACAD6| acyl-coenzyme A dehydrogenase, very long chain| CB1_000230008| D623_10021017| fb52d04| LCACD| MDA_GLEAN10018276| MVLCAD| N309_04576| PAL_GLEAN10010158| PANDA_013839| TREES_T100004068| Very-long-chain acyl-CoA dehydrogenase| Very long chain Acyl-Coa dehydrogenase| very-long-chain specific acyl-CoA dehydrogenase| Very long-chain specific acyl-CoA dehydrogenase, mitochondrial| vlcad| VLCAD very-long-chain acyl-CoA dehydrogenase| acadvl

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