The Function of ABCC5
Acts as a multispecific organic anion pump which can transport nucleotide analogs.
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Protein names
Recommended name:
Multidrug resistance-associated protein 5Short name:
SMRPAlternative name(s):
ATP-binding cassette sub-family C member 5Multi-specific organic anion transporter C
MOAT-C
pABC11
- RS1401999 (ABCC5) ??
- RS7620457 (ABCC5) ??
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Top Gene-Substance Interactions
ABCC5 Interacts with These Diseases
| Disease | Score |
Substances That Increase ABCC5
| Substances | Interaction | Organism | Category |
Substances That Decrease ABCC5
| Substances | Interaction | Organism | Category |
Conditions with Increased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Conditions with Decreased Gene Activity
| Condition | Change (log2fold) | Comparison | Species | Experimental variables | Experiment name |
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Technical
The following transcription factors affect gene expression:
Tissue specificity:
All isoforms are equally expressed in retina.
Molecular Function:
- Atp Binding
- Organic Anion Transmembrane Transporter Activity
- Atpase-Coupled Anion Transmembrane Transporter Activity
Biological Processes:
Drug Bank:
- Mercaptopurine
- Rifampicin
- Adefovir Dipivoxil
- Alprostadil
- Atorvastatin
- Cisplatin
- Dinoprostone
- Dipyridamole
- Glutathione
- Probenecid
- Sildenafil
- Sulfinpyrazone
- Zidovudine
- Fluorouracil