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  3. ABCC5

ABCC5 (ATP binding cassette subfamily C member 5)

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The Function of ABCC5

Acts as a multispecific organic anion pump which can transport nucleotide analogs.

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Protein names

Recommended name:

Multidrug resistance-associated protein 5

Short name:

SMRP

Alternative name(s):

ATP-binding cassette sub-family C member 5
Multi-specific organic anion transporter C
MOAT-C
pABC11

ABCC5 SNPs

    To see your genotype, you should be logged in and have a file with your genotype uploaded.

  1. RS1401999 (ABCC5) ??
  2. RS7620457 (ABCC5) ??

Top Gene-Substance Interactions

ABCC5 Interacts with These Diseases

Disease Score

Substances That Increase ABCC5

Substances Interaction Organism Category

Substances That Decrease ABCC5

Substances Interaction Organism Category

Conditions with Increased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Conditions with Decreased Gene Activity

Condition Change (log2fold) Comparison Species Experimental variables Experiment name

Technical

The following transcription factors affect gene expression:

  • p53

Tissue specificity:

All isoforms are equally expressed in retina.

Gene Pathways:

  • Metabolism
  • Disease
  • Transmembrane transport of small molecules
  • ABC transporters

Molecular Function:

  • Atpase-Coupled Anion Transmembrane Transporter Activity
  • Atp Binding
  • Organic Anion Transmembrane Transporter Activity

Biological Processes:

  • Hyaluronan Biosynthetic Process
  • Transmembrane Transport
  • Transport

Drug Bank:

  • Mercaptopurine
  • Rifampicin
  • Adefovir Dipivoxil
  • Alprostadil
  • Atorvastatin
  • Cisplatin
  • Dinoprostone
  • Dipyridamole
  • Glutathione
  • Probenecid
  • Sildenafil
  • Sulfinpyrazone
  • Zidovudine
  • Fluorouracil
*synonyms

Synonyms/Aliases/Alternative Names of the Gene:

hypothetical protein| ABC33| Abcc5a| Abcc5b| Anapl_05742| AS27_10226| ATP-binding cassette, sub-family C (CFTR/MRP), member 5| ATP-binding cassette, subfamily C (CFTR/MRP), member 5| ATP-binding cassette sub-family C (CFTR/MRP) member 5a| ATP-binding cassette, sub-family C (CFTR/MRP), member 5a| ATP-binding cassette, sub-family C (CFTR/MRP), member 5b| ATP-binding cassette sub-family C member 5| ATP-binding cassette, sub-family C , member 5| ATP-binding cassette, sub-family C, member 5| ATP-binding cassette, sub-family C, member 5 isoform 1 isoform 1-like protein| canalicular multispecific organic anion transporter C| CB1_001005015| D623_10006347| EST277145| fj51h02| H920_05403| M91_03620| moatc| MOAT-C| mrp5| Multidrug resistance-associated protein 5| multi-specific organic anion transporter C| N301_05124| N303_10277| N305_01862| N307_05255| N309_13060| N312_01830| N320_10452| N324_07469| N325_04147| N326_08094| N327_12881| N328_01773| N330_00671| N331_05072| N332_12102| N333_06467| N334_03454| N335_12504| N336_06816| N339_09918| N340_01698| pABC11| PAL_GLEAN10018179| PANDA_003758| smrp| Y956_07140| abcc5

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